Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 7, Problem 44TQ
Summary Introduction
To review:
The structural feature ofglucuronic acid thatincreases the solubility of steroid when attached to it.
Introduction:
Glucuronic acid is the monosaccharide derivative of glucose. The CH2OH terminal of glucose molecule undergoes oxidation, which results in the formation of glucuronic acid. The steroid is a lipid-soluble molecule derived from cholesterol. Steroids combine withglucuronic acid to increase its solubility in water.
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Fura-2 Fluorescence (Arbitrary Unit)
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[Ca2+]=2970nM, 25°C
[Ca2+] 2970nM, 4°C
[Ca2+]=0.9nM, 25°C
[Ca2+] = 0.9nM, 4°C
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Wavelength (nm)
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<
The figure on the LHS shows the excitation spectra of Fura-2 (Em
= 510 nm) in 2 solutions with two different Ca2+ ion concentration
as indicated. Except for temperature, the setting for excitation &
signal acquisition was identical.<
ப
a) The unit in Y-axis is arbitrary (unspecified). Why? <
<
b) Compare & contrast the excitation wavelength of the Isosbestic
Point of Fura-2 at 25 °C & 4 °C. Give a possible reason for the
discrepancy. <
c) The fluorescence intensity at 25 °C & 4 °C are different. Explain
why with the concept of electronic configuration. <
Chapter 7 Solutions
Biochemistry: The Molecular Basis of Life
Ch. 7 - Prob. 1QCh. 7 - Prob. 2QCh. 7 - Prob. 3QCh. 7 - Prob. 4QCh. 7 - Prob. 5QCh. 7 - Prob. 6QCh. 7 - Prob. 7QCh. 7 - Prob. 1RQCh. 7 - Prob. 2RQCh. 7 - Prob. 3RQ
Ch. 7 - Prob. 4RQCh. 7 - Prob. 5RQCh. 7 - Prob. 6RQCh. 7 - Prob. 7RQCh. 7 - Prob. 8RQCh. 7 - Prob. 9RQCh. 7 - Prob. 10RQCh. 7 - Prob. 11RQCh. 7 - Prob. 12RQCh. 7 - Prob. 13RQCh. 7 - Prob. 14RQCh. 7 - Prob. 15RQCh. 7 - Prob. 16RQCh. 7 - Prob. 17RQCh. 7 - Prob. 18RQCh. 7 - Prob. 19RQCh. 7 - Prob. 20RQCh. 7 - Prob. 21RQCh. 7 - Prob. 22RQCh. 7 - Prob. 23RQCh. 7 - Prob. 24RQCh. 7 - Prob. 25RQCh. 7 - Prob. 26RQCh. 7 - Prob. 27RQCh. 7 - Prob. 28FBCh. 7 - Prob. 29FBCh. 7 - Prob. 30FBCh. 7 - Prob. 31FBCh. 7 - Prob. 32FBCh. 7 - Prob. 33FBCh. 7 - Prob. 34FBCh. 7 - Prob. 35FBCh. 7 - Prob. 36FBCh. 7 - Prob. 37FBCh. 7 - Prob. 38SACh. 7 - Prob. 39SACh. 7 - Prob. 40SACh. 7 - Prob. 41SACh. 7 - Prob. 42SACh. 7 - Prob. 43TQCh. 7 - Prob. 44TQCh. 7 - Prob. 45TQCh. 7 - Prob. 46TQCh. 7 - Prob. 47TQCh. 7 - Prob. 48TQCh. 7 - Prob. 49TQCh. 7 - Prob. 50TQCh. 7 - Prob. 51TQCh. 7 - Prob. 52TQCh. 7 - Prob. 53TQCh. 7 - Prob. 54TQCh. 7 - Prob. 55TQCh. 7 - Prob. 56TQCh. 7 - Prob. 57TQCh. 7 - Prob. 58TQCh. 7 - Prob. 59TQCh. 7 - Prob. 60TQCh. 7 - Prob. 61TQCh. 7 - Prob. 62TQCh. 7 - Prob. 63TQCh. 7 - Prob. 64TQCh. 7 - Prob. 65TQCh. 7 - Prob. 66TQCh. 7 - Prob. 67TQCh. 7 - Prob. 68TQCh. 7 - Prob. 69TQCh. 7 - Prob. 70TQ
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