Chapter 4, Problem 1RE

Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing ${\text{Na}}^{\text{+}}$ and ${\text{K}}^{+}$ gates during the generation of an action potential. (True or false?)

Summary Introduction

To Determine:

If the given statement 'conformational modifications in channel proteins that are brought about by voltage variations are responsible for opening and closing sodium and potassium gates during the production of an action potential' is true or false.

Introduction:

An action potential can be defined as a quick rise and a subsequent decrease in voltage or membrane potential through a cellular membrane with a distinguishing pattern. Synapse is a junction present between the two neurons.

Answer to Problem 1RE

The given statement is true.

Explanation of Solution

The variations in the membrane potential generally influence the opening or closing of the voltage-gated channels. When there occur conformational modifications in channel proteins by the voltage variations. These modified channel proteins are responsible for the opening and closing of sodium and potassium gates during the production of an action potential.

So, action potentials are produced by particular types of voltage-gated ion channels that are embedded in the plasma membrane.

Conclusion

The given statement is true.