There is currently a H5N1 cattle outbreak in North America.According to the CDC on Feb 26*: "A multistate outbreak of HPAI A(H5N1) bird flu in dairy cows was first reported on March 25, 2024. This is the first time that these bird flu viruses had been found in cows. In the United States, since 2022, USDA has reported HPAI A(H5N1) virus detections in more than 200 mammals."List and describe two mechanisms that could lead to this H5N1 influenza strain evolving to spread in human: Mechanisms 1:Mechanisms 2:For the mutations to results in a human epidered they would need to change how the virus interacts with the human host. In the case of mutations that may promote an epidemic, provide an example for:a protein that might incur a mutation:how the mutation would change interactions with cells in the respiratory tract (name the receptor on human cells)List two phenotypic consequence from this mutation that would increase human risk

Two Evolutionary Mechanisms for H5N1 to Spread in HumansMechanism 1: Antigenic Drift (Gradual Point…

Answered: There is currently a H5N1 cattle…

Case Studies In Health Information Management

3rd Edition

ISBN:9781337676908

Author:SCHNERING

Publisher:SCHNERING

Chapter7: Healthcare Statistics And Research Methods

Section: Chapter Questions

Problem 7.10.1C

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There is currently a H5N1 cattle outbreak in North America.

According to the CDC on Feb 26*: "A multistate outbreak of HPAI A(H5N1) bird flu in dairy cows was first reported on March 25, 2024. This is the first time that these bird flu viruses had been found in cows. In the United States, since 2022, USDA has reported HPAI A(H5N1) virus detections in more than 200 mammals."

List and describe two mechanisms that could lead to this H5N1 influenza strain evolving to spread in human:

Mechanisms 1:
Mechanisms 2:

For the mutations to results in a human epidered they would need to change how the virus interacts with the human host. In the case of mutations that may promote an epidemic, provide an example for:

a protein that might incur a mutation:
how the mutation would change interactions with cells in the respiratory tract (name the receptor on human cells)
List two phenotypic consequence from this mutation that would increase human risk

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