2. (10 points) 8-oxoguanine, drawn below, can be generated from the reaction of guanine with reactive oxygen species (ROS). Once formed, 8-oxoguanine can form a base pair with adenine. Draw a Hoogsteen-type hydrogen bonding pattern of 8-oxoguanine with A. H₂N N N-H Page 1 of 3

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2. (10 points) 8-oxoguanine, drawn below, can be generated from the reaction of
guanine with reactive oxygen species (ROS). Once formed, 8-oxoguanine can
form a base pair with adenine. Draw a Hoogsteen-type hydrogen bonding pattern
of 8-oxoguanine with A.
H₂N
N
N-H
Page 1 of 3
Transcribed Image Text:2. (10 points) 8-oxoguanine, drawn below, can be generated from the reaction of guanine with reactive oxygen species (ROS). Once formed, 8-oxoguanine can form a base pair with adenine. Draw a Hoogsteen-type hydrogen bonding pattern of 8-oxoguanine with A. H₂N N N-H Page 1 of 3
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