Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 8, Problem 16QP
A beginning genetics student is attempting to complete an assignment to draw a base pair from a DNA molecule. The drawing is incomplete, and the student does not know how to finish. He asks for your advice. The assignment sheet shows that the drawing is to contain three hydrogen bonds, a purine, and a pyrimidine. From your knowledge of the pairing rules and the number of hydrogen bonds in A/T and G/C base pairs, what base pair do you help the student draw?
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A and B (adnine, cytosine, guanine, thymine)
C and D (G1, G2, G3, G4)
Choose all of the statements that correctly describe the base pairs drawn below.
A
C
H
H-N
-H-N
N-H- -N
B
H
D
موعة Rita
N
-H----
2
NHN
O-
-H-N
H
-H-
N- -H-N
The non-Watson-Crick base pair shown in A is much less stable than the base
pairs shown in B and C, because the smaller size of the two pyrimidine bases
induces a distortion in the structure of the double helix that decreases the
stability of the helix when compared to helices with the normal Watson-Crick
base pairs.
The base pair shown in B is found in BOTH DNA and RNA
The base pair shown in C is found ONLY in RNA and NOT DNA
The base pair seen in B is more stable than the Watson-Crick base pair shown in
C partly because of a larger number of hydrogen bonds and partly because of
more favourable pi-stacking interactions with adjacent base pairs.
Design a pair of primers to amplify the entire length of the following 45 base pair sequence.Make each primer 14 bases long. Write the sequences of the primers in 5' to 3' order.(Hint: It will help for you to write out BOTH strands of the DNA sequence listed below.5'-GATGCCCGTTGGATAAATTGGGCGTCTAGAATCGGTCACACTTAG-3'
Chapter 8 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 8.4 - Two genes associated with breast cancer, BRCA1 and...Ch. 8.4 - Prob. 2GRCh. 8 - What are Bruces options at this point? Bruce and...Ch. 8 - Should he reconsider and try chemotherapy instead?...Ch. 8 - Should he go ahead and enroll on the chance that...Ch. 8 - Until 1944, which cellular component was thought...Ch. 8 - Why do you think nucleic acids were originally not...Ch. 8 - Prob. 3QPCh. 8 - In the experiments of Aery, MacLeod, and McCarty,...Ch. 8 - Read the following experiment and interpret the...
Ch. 8 - Recently, scientists discovered that a rare...Ch. 8 - List the pyrimidine bases, the purine bases, and...Ch. 8 - In analyzing the base composition of a DNA sample,...Ch. 8 - The basic building blocks of nucleic acids are: a....Ch. 8 - Adenine is a: a. nucleoside b. purine c....Ch. 8 - Polynucleotide chains have a 5 and a 3 end. Which...Ch. 8 - DNA contains many hydrogen bonds. Are hydrogen...Ch. 8 - Prob. 13QPCh. 8 - State the properties of the WatsonCrick model of...Ch. 8 - Using Figures 8.7 and 8.9 as a guide, draw a...Ch. 8 - A beginning genetics student is attempting to...Ch. 8 - Chemical analysis shows that a nucleic acid sample...Ch. 8 - Prob. 18QPCh. 8 - RNA is ribonucleic acid, and DNA is...Ch. 8 - What is the function of DNA polymerase? a. It...Ch. 8 - Which of the following statements is not true...Ch. 8 - Make the complementary strand for the following...Ch. 8 - How does DNA replication occur in a precise manner...Ch. 8 - Nucleosomes are complexes of: a. RNA and DNA b....Ch. 8 - Discuss the levels of chromosomal organization...
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- Describe the theoretical structure for deoxyribonucleic acid. Specifically, describe the attributes (features) of the Watson and Crick model for DNA. I cant figure out where to begin this for my homework.arrow_forwardYou have to label the numbers. Then the last two parts are just names.arrow_forwardHow many different 8-mer sequences of DNA are there?arrow_forward
- In 1950, Edwin Chargaff discovered that the ratios of A:T bases, and of G:C bases, in DNA is always 1:1. This discovery became known as Chargaff's rules and was important in helping determine the structure of DNA. The percentages of adenine (A), cytosine (C), guanine (G) and thymine (T) bases in DNA from three species are shown below. Select the best answer for each of the questions. Q1: Does the distribution of nucleotide bases in species 1 and 2 in the table follow Chargaff’s rules? Why or why not? Q2: Based on the information in the table, what is the % cytosine in species 3?arrow_forwardHow many adenine bases are there if there are eight thousand cytosine bases in a fifteen thousand bp DNA?arrow_forwardUsing the first and second base key below, predict the DNA sequence given by the SOLID color sequence. For the key G = green, R = red, Y = yellow, and B = blue. Note that the first base of the sequence is already given ("A"). Give the remaining 8 bases for this sequence. A First base A CCT Second base A CGT BGY R GBRY RBG R Y (G) B Y G)(R) GB )( R )( Y ) ( G) Barrow_forward
- Please explain why the order is 3–1-4-2 and not another way, thank you so much. Question is in the image.arrow_forwardThere are seven common terms usually encountered in the discussion of DNA and the Central Dogma of Molecular Genetics. Find at least 5 of these common terms that these will serve as the introductory terms to understand further this module. Locate and identify them by shading the letters with the color of your choice. Describe or define each term as you identify them.arrow_forwardThe two sides of the DNA double helix are connected by pairs of bases (adenine, thymine, cytosine, and guanine). Because of the geometric shape of these molecules, adenine bonds with thymine and cytosine bonds with guanine. The figure (Figure 1) shows the thymine-adenine bond. Each charge shown is ±e, and the H−N distance is 0.110 nm . Calculate the net force that thymine exerts on adenine. To keep the calculations fairly simple, yet reasonable, consider only the forces due to the O−H−N and the N−H−N combinations, assuming that these two combinations are parallel to each other. Remember, however, that in the O−H−N set, the O− exerts a force on both the H+ and the N−, and likewise along the N−H−N set. Express your answer in newtons. Is the net force attractive or repulsive?arrow_forward
- What is the methyl group-containing nucleobase composition of a double- stranded eukaryotic DNA with 52,000 bases that contains 22% bicyclic nucleobases characterized to have both an amino group and a keto group? (Instructions: Do NOT put spaces or commas or additional words/letters/units; Type in your answer in NUMERICAL FORM with the following format: 1234567)arrow_forwardI need help because i don't get it. Can you help me to explain to me, please?arrow_forwardThe Bacteria Escherichia coli DNA genome has a molecular mass of about 3.1 X 10° D. In your answers, show how you came up to each result? (a) How many base pairs does this bacterium contain? (b) How many full double-helical turns does this DNA contain? (c) How long is this DNA in um?arrow_forward
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