Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 8, Problem 13QP
Summary Introduction
Introduction: It was understood during the 1940s that DNA carries genetic information and it is the transforming factor in bacterial cells. Watson and Crick also began their work on this prospect in the early 1950s.
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In the Watson-Crick structure of DNA, the:
a. adenine content of one strand must equal the thymine content of the same strand.
b. nucleotides are arranged in the A-form.
c. purine content (fraction of bases that are purines) must be the same in both strands.
d. two strands are parallel.
e. the strands are complementary to each other.
In Watson and Crick's model of DNA structure, the two strands of the DNA double helix are joined through
a.
Ionic bonds
b.
Hydrophobic interactions
c.
Covalent bonds
d.
Disulfide bonds
e.
Hydrogen bonds
How will each of the following substances or conditions affect DNA structure? a. ethanol; b. heat; c. dimethylsulfate; d. nitrous acid; e. 5-BU
Chapter 8 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 8.4 - Two genes associated with breast cancer, BRCA1 and...Ch. 8.4 - Prob. 2GRCh. 8 - What are Bruces options at this point? Bruce and...Ch. 8 - Should he reconsider and try chemotherapy instead?...Ch. 8 - Should he go ahead and enroll on the chance that...Ch. 8 - Until 1944, which cellular component was thought...Ch. 8 - Why do you think nucleic acids were originally not...Ch. 8 - Prob. 3QPCh. 8 - In the experiments of Aery, MacLeod, and McCarty,...Ch. 8 - Read the following experiment and interpret the...
Ch. 8 - Recently, scientists discovered that a rare...Ch. 8 - List the pyrimidine bases, the purine bases, and...Ch. 8 - In analyzing the base composition of a DNA sample,...Ch. 8 - The basic building blocks of nucleic acids are: a....Ch. 8 - Adenine is a: a. nucleoside b. purine c....Ch. 8 - Polynucleotide chains have a 5 and a 3 end. Which...Ch. 8 - DNA contains many hydrogen bonds. Are hydrogen...Ch. 8 - Prob. 13QPCh. 8 - State the properties of the WatsonCrick model of...Ch. 8 - Using Figures 8.7 and 8.9 as a guide, draw a...Ch. 8 - A beginning genetics student is attempting to...Ch. 8 - Chemical analysis shows that a nucleic acid sample...Ch. 8 - Prob. 18QPCh. 8 - RNA is ribonucleic acid, and DNA is...Ch. 8 - What is the function of DNA polymerase? a. It...Ch. 8 - Which of the following statements is not true...Ch. 8 - Make the complementary strand for the following...Ch. 8 - How does DNA replication occur in a precise manner...Ch. 8 - Nucleosomes are complexes of: a. RNA and DNA b....Ch. 8 - Discuss the levels of chromosomal organization...
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- State the properties of the WatsonCrick model of DNA in the following categories: a. number of polynucleotide chains b. polarity (running in same direction or opposite directions) c. bases on interior or exterior of molecule d. sugar/phosphate on interior or exterior of molecule e. which bases pair with which f. right- or left-handed helixarrow_forwardWhich of the following items do not affect the melting temperature of DNA? A) length of the DNA the type of polymerase used to amplify the DNA (C) salt content surrounding the DNA D) nucleotide composition of the DNA E) the type of DNA (genomic versus CDNA)arrow_forwardWhich of the following statements are TRUE?I. DNA replication is a semiconservative process wherein the two resulting double helices consist of one new strand and one parental strand.II. The DNA strand that is used to make a complementary daughter strand is called the parental strand.III. The precursor of each new nucleotide in the DNA strand is a deoxynucleoside 3′-triphosphate.IV. The incoming nucleotide always attaches to 5′-phosphate of the previously added nucleotide a. I only b. II only c. I and IV d. III and IVarrow_forward
- Which of the following statements are TRUE?I. DNA replication is a semiconservative process wherein the two resulting double helices consist of one new strand and one parental strand.II. The DNA strand that is used to make a complementary daughter strand is called the parental strand.III. The precursor of each new nucleotide in the DNA strand is a deoxynucleoside 3′-triphosphate.IV. The incoming nucleotide always attaches to 5′-phosphate of the previously added nucleotidearrow_forwardWhich of the following is true regarding the 5’ vs. the 3’ end of a strand of DNA? a) only double-stranded DNA can have a 5' and a 3' end b) 5' and 3' are designations of the carbon in the deoxyribose of a nucleotide that is not bound to another deoxyribose or phosphate group c) 5' and 3' are designations of the DNA base that is unbound to another base d) The 5' end of DNA is always considered the start of the gene and the 3' end is considered the endarrow_forwardWatson and Crick used an approach called model building to deduce the structure of the DNA double helix.How does this differ from the more conventional experimental approach that is undertaken in a research laboratory? In this regard, why was the experiment of Meselsonand Stahl considered to be of such critical importance?arrow_forward
- Which of the following is true about the structure of DNA as proposed by Watson and Crick (B-form DNA)? A. DNA forms a left-handed double helix. B. The strands of DNA are parallel. C. The complementary base pairs are held together by hydrogen bonds. D. A complete turn of the double helix occurs after every base pair.arrow_forward8)arrow_forwardIndicate whether each of the following statements about the double-helix secondary structure of DNA is true or false. a. The two polynucleotide strands are complementary rather than identical. b. Bases present extend outward from the double helix. c. Covalent bonding occurs between the two polynucleotide strands. d. The two polynucleotide strands run in the 5′-to-3′ directionarrow_forward
- (1) A scientist discovers an unknown nucleic acid, they analyze it chemically and discover the following: 22% of the nitrogenous bases contain adenine, 40% contain guanine, 20% contain thymine and 18% contain cytosine. Based only on this information, this nucleic acid must be: a. Single-Stranded DNA b. Single-stranded RNA c. Double-Stranded DNA d. Double- stranded RNA (2) In a double-stranded molecule of DNA which of the following ratios should equal 1? (pick 3) a. A/C b. (A+T) / (G+C) c. (A+G) / (C + T) d. purines/ pyrimidines e. G/C (3) why is DNA replication is said to be bidirectional ?arrow_forwardWhich statement below best describes what these data might have demonstrated to Kornberg about the process of replication? CHOOSE ONE and explain the rationale behind your answer in a minimum of four sentences. A. Products of replication are DNA polymers. B. DNA Pol I-mediated replication is a high-fidelity (i.e., no mistakes) process C. DNA Pol III-mediated replication gives rise to two daughter strands, one which is made of only the original templates, and one of which is only newly synthesized polymer. D. In DNA, all 4 classes of nitrogenous bases are more or less equally represented E. A pairs with T and C pairs with Garrow_forwarda) Explain the effect of the guanine:cytosine ratio on melting temperature of DNA. b) The Hershey-Chase experiment proved that DNA is the genetic material and not protein. Explain in detatil how this experiment was conducted.arrow_forward
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