Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 24, Problem 11P
Interpretation Introduction
Interpretation:
The number of ATP equivalents needed to perform palmitic acid from acetyl CoA should be determined.
Concept Introduction:
The steps in the synthesis of palmitoyl CoA and the synthesis of malonyl CoA are as follows:
The overall reaction for the synthesis of palmitoyl CoA from acetyl CoA is,
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Palmitoleic acid, 16:1Δ⁹ hexadecaenoic acid, (16 carbon FA with one double bond )is an important fatty acid component of TAGs and cell membranes. Briefly explain the process of beta oxidation of this fatty acid and the number (only) of FADH, NADH and acetyl CoA outcome. What is the total ATP (only number) generated from this fatty acid after beta oxidation.
For beta-oxidation of an 18:1 oleate mono-unsaturated fatty acid:
- How many Acetyl CoA produced?
- How many NADH produced?
- How many FADH2 produced?
And explain why FADH2 and NADH are different; when they would be the same number in the beta-oxidation for saturated fatty acids.
ATP Accounting
Upon digestion of starch, maltose, one of its degradation products, is further hydrolyzed into its monosaccharide components prior to
intestinal absorption and entry into the glycolysis. Calculate the number of ATP molecules produced from the digestion and complete
oxidation of 3 molecules of maltose considering the malate-aspartate shuttle. Answer the following items using numerical value
only (e.g. 1, not "1 ATP") which will help you arrive at the final answer for this question.
a. Total number of glucose molecules entering glycolysis:
b. Total number of pyruvate molecules produced at the end of glycolysis:
c. Total number of mitochondrial NADH produced after pyruvate is acted upon by the pyruvate dehydrogenase complex:
d. Total number of CO2 released right after the pyruvate dehydrogenase complex reaction:
e. Total number of acetyl CoA molecules entering the citric acid cycle:
f. Total number of net cytosolic ATP molecules produced right after glycolysis:
g. Total…
Chapter 24 Solutions
Biochemistry
Ch. 24 - Explaining the Stoichiometry of Fatty Acid...Ch. 24 - Tracing Carbon Atom Incorporation in Fatty Acids...Ch. 24 - Modeling the Regulation of AcetyI-CoA Carboxylase...Ch. 24 - Prob. 4PCh. 24 - Prob. 5PCh. 24 - Prob. 6PCh. 24 - Understanding the Stoichiometry of Cholesterol...Ch. 24 - Prob. 8PCh. 24 - Prob. 9PCh. 24 - Prob. 10P
Ch. 24 - Prob. 11PCh. 24 - Understanding the Mechanism of the...Ch. 24 - Prob. 13PCh. 24 - Understanding the Mechanism of the HMC-CoA...Ch. 24 - Prob. 15PCh. 24 - Prob. 16PCh. 24 - Prob. 17PCh. 24 - Prob. 18PCh. 24 - Prob. 19PCh. 24 - Prob. 20PCh. 24 - Prob. 21PCh. 24 - Prob. 22PCh. 24 - Prob. 23PCh. 24 - Prob. 24PCh. 24 - Prob. 25P
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