A balanced stoichiometric reaction for the synthesis of phosphatidylethanolamine from glycerol, fatty acyl-CoA and ethanolamine should be written and estimation for Δ G 0 ' for overall process should be made. Concept Introduction: phosphatidylethanolamine synthesis is a combination of two pathways. Phosphatidylethanolamine synthesis starts with phosphorylation of ethanolamine followed by transfer of cytidylyl group from CTP to form CDP-ethanolamine and pyrophosphate. Hydrolysis of this pyrophosphate drives this reaction forward. Then phosphoethanolamine is linked to the diacylglycerol backbone. This diacylglycerol backbone is synthesized by glycerol and fatty acids.

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Chapter 24, Problem 6P

Interpretation Introduction

Interpretation:

A balanced stoichiometric reaction for the synthesis of phosphatidylethanolamine from glycerol, fatty acyl-CoA and ethanolamine should be written and estimation for ΔG0' for overall process should be made.

Concept Introduction:

phosphatidylethanolamine synthesis is a combination of two pathways. Phosphatidylethanolamine synthesis starts with phosphorylation of ethanolamine followed by transfer of cytidylyl group from CTP to form CDP-ethanolamine and pyrophosphate. Hydrolysis of this pyrophosphate drives this reaction forward. Then phosphoethanolamine is linked to the diacylglycerol backbone. This diacylglycerol backbone is synthesized by glycerol and fatty acids.

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