Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 24, Problem 6P
Interpretation Introduction
Interpretation:
A balanced stoichiometric reaction for the synthesis of phosphatidylethanolamine from glycerol, fatty acyl-CoA and ethanolamine should be written and estimation for
Concept Introduction:
phosphatidylethanolamine synthesis is a combination of two pathways. Phosphatidylethanolamine synthesis starts with phosphorylation of ethanolamine followed by transfer of cytidylyl group from CTP to form CDP-ethanolamine and pyrophosphate. Hydrolysis of this pyrophosphate drives this reaction forward. Then phosphoethanolamine is linked to the diacylglycerol backbone. This diacylglycerol backbone is synthesized by glycerol and fatty acids.
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O positions a carbonyl group on carbon 2 of fructose-1-phosphate
O positions an amino group NH2 on carbon 3 of fructose-1-phosphate
O positions a carbonyl group on carbon 3 of fructose-1-phosphate
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Triose phosphate isomerase
In a key reaction of glycolysis, dihydroxyacetone phosphate (DHAP) is isomerized into
glyceraldehyde 3-phosphate (G3P) by the action of the enzyme triose phosphate isomerase:
CH₂OH
C=O
CH₂OPO3²-
DHAP
CHO
HC-OH
CH₂OPO3²-
G3P
AG°¹ +7.5 kJ/mol
Because AG is positive, the equilibrium lies to the left.
(a) Calculate the equilibrium constant for this reaction, assuming a temperature of 37 °C.
(b) In the cell, depletion of G3P makes the reaction proceed. What is the value of AG if the
concentration of G3P is kept at 1/100 of the value of the concentration of DHAP?
C
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+
Chapter 24 Solutions
Biochemistry
Ch. 24 - Explaining the Stoichiometry of Fatty Acid...Ch. 24 - Tracing Carbon Atom Incorporation in Fatty Acids...Ch. 24 - Modeling the Regulation of AcetyI-CoA Carboxylase...Ch. 24 - Prob. 4PCh. 24 - Prob. 5PCh. 24 - Prob. 6PCh. 24 - Understanding the Stoichiometry of Cholesterol...Ch. 24 - Prob. 8PCh. 24 - Prob. 9PCh. 24 - Prob. 10P
Ch. 24 - Prob. 11PCh. 24 - Understanding the Mechanism of the...Ch. 24 - Prob. 13PCh. 24 - Understanding the Mechanism of the HMC-CoA...Ch. 24 - Prob. 15PCh. 24 - Prob. 16PCh. 24 - Prob. 17PCh. 24 - Prob. 18PCh. 24 - Prob. 19PCh. 24 - Prob. 20PCh. 24 - Prob. 21PCh. 24 - Prob. 22PCh. 24 - Prob. 23PCh. 24 - Prob. 24PCh. 24 - Prob. 25P
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