Chapter 21, Problem 21.53P

(a)

Interpretation Introduction

Interpretation:

The synthesis of carbinoxamine has to be shown.

Concept introduction:

The Grignard reaction:

Alkyl, vinyl, or aryl-magnesium halides ($\text{RMgX}$) is called as Grignard reagent.

Grignard reagent is reaction with carbonyl compound such as aldehyde or ketone, produces corresponding alcohol is the product and it is the one of the carbon – carbon bond forming reaction.

(b)

Interpretation Introduction

Interpretation:

The chirality of Carbinoxamine is to be identified and the possible stereoisomers has to be identified in the given synthesis.

Concept introduction:

Chiral:

A molecule is non superimposable on its mirror image is called chiral molecule.

Four different atoms attached to a carbon atom is called chiral molecule.

Isomer:

A molecule having the same molecular formula but with different chemical structure is called isomer.

Stereoisomers:

Stereoisomers are molecules that have the same molecular formula and they differ only in arrangement of atom in three-dimensional space.

Enantiomers:

A compound which is non-superimposable mirror image is called enantiomers.

Diastereomers:

A compound which is non-superimposable and non-mirror image is called diastereomers.

Racemic mixture:

A racemic mixture is simply a mixture containing an equal amount of each enantiomer.