Given that the reaction of (S)-3-methyl-2-pentanone with methylmagnesium bromide followed by acidification yields 2,3-dimethyl-2-pentanol. The stereochemistry of the product is to be given and whether it is optically active or not is to be stated. Concept introduction: If during a reaction of an optically active compound a new chiral centre is created, it will lead to the formation of diastereomers in different proportions resulting in an optically active mixture. If a new chiral centre is not created then also the product will be optically active since the chirality of the other carbon remains unaffected during the course of the reaction. To give: The stereochemistry of the product, 2,3-dimethyl-2-pentanol, formed in the reaction of (S)-3-methyl-2-pentanone with methylmagnesium bromide followed by acidification. To state: Whether the product is optically active or not.

Question

H3C N- H₂NNH₂ H⭑ CH3 H3C IN CH3 Hydrazine reacts with 2,4-pentanedione to yield 3,5-dimethylpyrazole. Including protonations and deprotonations, the reaction takes 12 steps. Write out the mechanism on a sheet of paper and then draw the structure of the product of step 6. • You do not have to consider stereochemistry. •You do not have to explicitly draw H atoms. • Do not include lone pairs in your answer. They will not be considered in the grading. • In an elimination step, include the structure of the leaving group, but draw it in its own sketcher. Separate structures with + signs from the drop-down menu. ? Sn th Previous Next

Answer 1

Question

Chapter 17.SE, Problem 61AP

Interpretation Introduction

Interpretation:

Given that the reaction of (S)-3-methyl-2-pentanone with methylmagnesium bromide followed by acidification yields 2,3-dimethyl-2-pentanol. The stereochemistry of the product is to be given and whether it is optically active or not is to be stated.

Concept introduction:

If during a reaction of an optically active compound a new chiral centre is created, it will lead to the formation of diastereomers in different proportions resulting in an optically active mixture. If a new chiral centre is not created then also the product will be optically active since the chirality of the other carbon remains unaffected during the course of the reaction.

To give:

The stereochemistry of the product, 2,3-dimethyl-2-pentanol, formed in the reaction of (S)-3-methyl-2-pentanone with methylmagnesium bromide followed by acidification.

To state:

Whether the product is optically active or not.

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