The normal function of the proto-oncogenes and the way mutations in the proto-oncogenes contribute to the production of cancer. Introduction: Any change in the genetic material of an individual, which is of permanent nature, is referred to as mutation. One kind of mutation is base-pair mutation, which involves the alteration of a single base pair in the genetic material. There are two kinds of cells, namely tumor suppressor genes and proto-oncogenes.

Question

Identify two genetic mechanisms whereby proto-oncogenes can become overexpressed. Select the two mechanisms. Identify two genetic mechanisms whereby proto-oncogenes can become overexpressed.Select the two mechanisms. 1) alterations in chromatin structure 2) a gain-of-function alteration 3)modification of proto-oncogenes products 4)mutations that result in an abnormal protein product 5)mutations within gene-regulatory regions

Answer 1

Question

Chapter 16.5, Problem 3SB

Summary Introduction

To review:

The normal function of the proto-oncogenes and the way mutations in the proto-oncogenes contribute to the production of cancer.

Introduction:

Any change in the genetic material of an individual, which is of permanent nature, is referred to as mutation. One kind of mutation is base-pair mutation, which involves the alteration of a single base pair in the genetic material. There are two kinds of cells, namely tumor suppressor genes and proto-oncogenes.

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