Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 16.5, Problem 2SB
Summary Introduction

To review:

The normal function of the tumor suppressor gene and the way the mutations in the tumor suppressor genes contribute to the production of cancer.

Introduction:

Mutations are basically changes to the genetic material. One kind of mutation is base-pair mutation, which involves the alteration of a single base pair in the genetic material. Such mutations are known as point mutations. These mutations may lead to abnormalities or cancer.

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How tumor-suppressor genes contribute to cancer whenmutated or abnormally expressed ?
How can a mutation in a tumor-suppressor gene contribute to the development of cancer?
Can restoring tumor suppressor function, such as mutant p53 or pRb, be used to cure cancer? If that's the case, how is it possible?
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