
Concept explainers
(a)
Interpretation:
Whether the “production of citrate from oxaloacetate and acetyl CoA” in citrate-malate shuttle system occur in the mitochondrial matrix or in the cytosol has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.
Acetyl CoA is synthesized in mitochondria and then transported to cytosol through the citrate-malate shuttle system.
(b)
Interpretation:
Whether “ATP conversion to ADP” occurs in the mitochondrial matrix or in the cytosol in the citrate–malate shuttle system has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.
Acetyl CoA is synthesized in mitochondria and then transported to cytosol through the citrate-malate shuttle system.
(c)
Interpretation:
Whether “the production of acetyl CoA and oxaloacetate from citrate” occur in the mitochondrial matrix or in the cytosol in the citrate–malate shuttle system has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.
Acetyl CoA is synthesized in mitochondria and then transported to cytosol through the citrate-malate shuttle system.
(d)
Interpretation:
Whether “NADH is used as a reducing agent” in the mitochondrial matrix or in the cytosol in the citrate–malate shuttle system has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid.
Acetyl CoA is synthesized in mitochondria and then transported to cytosol through the citrate-malate shuttle system.

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Chapter 14 Solutions
Organic And Biological Chemistry
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