Whether “acyl CoA is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated. Concept introduction: The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH 2 , and NADH are produced in this reaction. The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane. The fatty acid is activated by CoA and ATP. The activated fatty acid-CoA is called acyl CoA. The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

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Answer 1

Question

Chapter 14, Problem 14.26EP

(a)

Interpretation Introduction

Interpretation:

Whether “acyl CoA is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane. The fatty acid is activated by CoA and ATP. The activated fatty acid-CoA is called acyl CoA.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(b)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine enters the inner mitochondrial membrane” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(c)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine is converted to carnitine” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(d)

Interpretation Introduction

Interpretation:

Whether “coenzyme A is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

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NH3 decomposes through an equilibrium reaction between NH3, H2, and N2. Only one of the options is correct:(A). The mechanism of the NH3 decomposition reaction must necessarily involve the collision of two NH3 molecules to induce a rearrangement of the atoms in this molecule.(B). The molecular weight of the NH3 decomposition reaction is 2 since two NH3 molecules must collide.(C). The rate of the NH3 decomposition reaction must be greater than that of NH3 synthesis, since the former requires two molecules to collide and the latter, four.(D). The NH3 decomposition reaction cannot occur in a single step.

Given the equilibrium A2 + B2 ⇌ 2 AB where k1 is the rate coefficient of the forward reaction and k-1 is the rate coefficient of the reverse reaction, with the forward reaction being first-order in A2 and B2, and the reverse reaction being second-order in AB. Equilibrium will be reached later if the relative values of the constants are:(A) k1 high and k-1 high(B) k1 high and k-1 low(C) k1 low and k-1 high(D) k1 low and k-1 low

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Answer 2

Question

Chapter 14, Problem 14.26EP

(a)

Interpretation Introduction

Interpretation:

Whether “acyl CoA is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane. The fatty acid is activated by CoA and ATP. The activated fatty acid-CoA is called acyl CoA.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(b)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine enters the inner mitochondrial membrane” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(c)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine is converted to carnitine” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(d)

Interpretation Introduction

Interpretation:

Whether “coenzyme A is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

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Answer 3

Question

Chapter 14, Problem 14.26EP

(a)

Interpretation Introduction

Interpretation:

Whether “acyl CoA is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane. The fatty acid is activated by CoA and ATP. The activated fatty acid-CoA is called acyl CoA.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(b)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine enters the inner mitochondrial membrane” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(c)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine is converted to carnitine” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(d)

Interpretation Introduction

Interpretation:

Whether “coenzyme A is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

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Answer 4

Question

Chapter 14, Problem 14.26EP

(a)

Interpretation Introduction

Interpretation:

Whether “acyl CoA is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane. The fatty acid is activated by CoA and ATP. The activated fatty acid-CoA is called acyl CoA.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(b)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine enters the inner mitochondrial membrane” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(c)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine is converted to carnitine” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(d)

Interpretation Introduction

Interpretation:

Whether “coenzyme A is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

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Answer 5

Chapter 14, Problem 14.26EP

(a)

Interpretation Introduction

Interpretation:

Whether “acyl CoA is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane. The fatty acid is activated by CoA and ATP. The activated fatty acid-CoA is called acyl CoA.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(b)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine enters the inner mitochondrial membrane” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(c)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine is converted to carnitine” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

(d)

Interpretation Introduction

Interpretation:

Whether “coenzyme A is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

Answer 6

Chapter 14, Problem 14.26EP

(a)

Interpretation Introduction

Interpretation:

Whether “acyl CoA is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane. The fatty acid is activated by CoA and ATP. The activated fatty acid-CoA is called acyl CoA.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

Answer 7

Chapter 14, Problem 14.26EP

(a)

Interpretation Introduction

Interpretation:

Whether “acyl CoA is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The first stage of fatty acid oxidation is the activation of fatty acids in the outer mitochondrial membrane. The fatty acid is activated by CoA and ATP. The activated fatty acid-CoA is called acyl CoA.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

Answer 8

(b)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine enters the inner mitochondrial membrane” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

Answer 9

(b)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine enters the inner mitochondrial membrane” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

Answer 10

(c)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine is converted to carnitine” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

Answer 11

(c)

Interpretation Introduction

Interpretation:

Whether “acyl carnitine is converted to carnitine” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

Answer 12

(d)

Interpretation Introduction

Interpretation:

Whether “coenzyme A is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

Answer 13

(d)

Interpretation Introduction

Interpretation:

Whether “coenzyme A is a product” in the mitochondrial matrix or in the mitochondrial intermembrane space in the carnitine shuttle system associated with the β-oxidation process has to be indicated.

Concept introduction:

The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acyl CoA is degraded to acetyl CoA. This pathway is termed as the β-oxidation pathway. Acetyl CoA, FADH₂, and NADH are produced in this reaction.

The enzymes that are needed for the oxidation of fatty acid are located in the mitochondrial matrix. Acyl CoA cannot pass through the inner mitochondrial membrane to the mitochondrial matrix because it is too large. A shuttle mechanism that involves the molecule carnitine effects the entry of acyl CoA into the mitochondrial matrix.

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Ch. 14.1 - Which of the following statements about digestion...Ch. 14.1 - Prob. 2QQ Ch. 14.1 - The major function of bile released during...Ch. 14.1 - The two major products of triacylglycerol...Ch. 14.1 - Prob. 5QQ Ch. 14.2 - Hormone-sensitive lipase needed for...Ch. 14.2 - Prob. 2QQ Ch. 14.2 - Which of the following is not a product of...Ch. 14.3 - Prob. 1QQ Ch. 14.3 - What is the intermediate compound in the two-step...

Solution Summary: The author explains that acyl CoA is a product in the mitochondrial matrix, and the carnitine shuttle system associated with the -oxidation process.

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