The following diagram show what is required for an active promoter of a gene of interest, where:A1 = Activator 1A2 = Activator 2Med = MediatorRep = Repressor Based on the following data, predict: Chromatin conformation Methylation state of the proximal promoter If protein A1 is present or absent If protein A2 is present or absent If the mediator is present or absent If the repressor is absence or present If this gene is likely to be transcribed or notPlease note that this is an "all or nothing" bonus question, and no partial credit will be awarded. Selecting all answers will result in zero points awarded. Selecting at least one incorrect answer will result in zero points being awarded. Question 28 options: Euchromatin Heterochromatin Methylated promoter Unmethylated promoter Activator A1 present Activator A1 absent Activator A2 present Activator A2 absent Mediator present Mediator absent Repressor present Repressor not present Transcription is likely Transcription is unlikely
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
Transformation Experiment in Bacteria
In the discovery of genetic material, the experiment conducted by Frederick Griffith on Streptococcus pneumonia proved to be a stepping stone.
Plasmids and Vectors
The DNA molecule that exists in a circular shape and is smaller in size which is capable of its replication is called Plasmids. In other words, it is called extra-chromosomal plasmid DNA. Vectors are the molecule which is capable of carrying genetic material which can be transferred into another cell and further carry out replication and expression. Plasmids can act as vectors.
The following diagram show what is required for an active promoter of a gene of interest, where:
A1 = Activator 1
A2 = Activator 2
Med = Mediator
Rep = Repressor
Based on the following data, predict:
- Chromatin conformation
- Methylation state of the proximal promoter
- If protein A1 is present or absent
- If protein A2 is present or absent
- If the mediator is present or absent
- If the repressor is absence or present
If this gene is likely to be transcribed or not
Please note that this is an "all or nothing" bonus question, and no partial credit will be awarded. Selecting all answers will result in zero points awarded. Selecting at least one incorrect answer will result in zero points being awarded.
Question 28 options:
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Euchromatin |
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Heterochromatin |
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Methylated promoter |
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Unmethylated promoter |
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Activator A1 present |
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Activator A1 absent |
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Activator A2 present |
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Activator A2 absent |
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Mediator present |
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Mediator absent |
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Repressor present |
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Repressor not present |
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Transcription is likely |
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Transcription is unlikely |
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