First Base Codons Found in Messenger RNA Second Base U C A G Phe Ser Tyr Cys Phe Ser Tyr Cys U Leu Ser Stop Stop A Leu Ser Stop Trp Leu Pro His Leu Pro His с Leu Pro Leu Pro 등등 Gln Gln ខខខខ Arg Arg Arg Arg lle Thr Asn Ser A lle Thr Asn Ser lle Thr Lys Arg Met Thr Lys Arg Val Ala Asp Gly Val Ala Asp Gly G Val Ala Glu Gly UGAGUGAGUGAGUCAG с А Val Ala Glu Gly Third Base

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter29: Transcription And The Regulation Of Gene Expression
Section: Chapter Questions
Problem 16P
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1) Given an mRNA with the following sequence, please translate the codons to a chain of amino acids. Use the codon chart below.

5’AUG/CCU/GCU/UAC/CGG/GAG/UAA3’

“met-_________-_________-_________-_________-_________”STOP”

 

2) Assuming the original polypeptide chain below, match each type of point mutation with the polypeptide chain that results.

 

Original polypeptide: Pro-Thr-Ser-Leu-Leu-His-Asn

A.    Missense

B.    Silent

C.     Nonsense

D.    Frameshift

 

______ Pro-Thr-Ser-STOP

 

 

______ Pro-Thr-Ser-Leu-Ile-His-Asn

 

 

______ Pro-Thr-Ser-Leu-Leu-His-Asn

 

 

_______ Pro-Thr-His-Cys-Tyr-Thr

First Base
Codons Found in Messenger RNA
Second Base
U C A
G
Phe
Ser
Tyr
Cys
Phe
Ser
Tyr
Cys
U
Leu
Ser
Stop
Stop A
Leu
Ser
Stop
Trp
Leu
Pro
His
Leu
Pro
His
с
Leu
Pro
Leu
Pro
등등
Gln
Gln
ខខខខ
Arg
Arg
Arg
Arg
lle
Thr
Asn
Ser
A
lle
Thr
Asn
Ser
lle
Thr
Lys
Arg
Met
Thr
Lys
Arg
Val
Ala
Asp
Gly
Val
Ala
Asp
Gly
G
Val
Ala
Glu
Gly
UGAGUGAGUGAGUCAG
с
А
Val
Ala
Glu
Gly
Third Base
Transcribed Image Text:First Base Codons Found in Messenger RNA Second Base U C A G Phe Ser Tyr Cys Phe Ser Tyr Cys U Leu Ser Stop Stop A Leu Ser Stop Trp Leu Pro His Leu Pro His с Leu Pro Leu Pro 등등 Gln Gln ខខខខ Arg Arg Arg Arg lle Thr Asn Ser A lle Thr Asn Ser lle Thr Lys Arg Met Thr Lys Arg Val Ala Asp Gly Val Ala Asp Gly G Val Ala Glu Gly UGAGUGAGUGAGUCAG с А Val Ala Glu Gly Third Base
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