Huntington's disease is an autosomal dominant disorder caused by a gradual build up of a misfolded protein in the brain. a 45 year old man finds out that he has Huntington's which his father died from but he knows his mother never developed the disease and lived to be 90. He is married with one daughter and his wife doesn't have the disease. What are the chances that his daughter develop Huntington? 25%, 50%, 75%, 100% or cannot tell from the information

Huntington's disease is an autosomal dominant disorder caused by a gradual build up of a misfolded protein in the brain. a 45 year old man finds out that he has Huntington's which his father died from but he knows his mother never developed the disease and lived to be 90. He is married with one daughter and his wife doesn't have the disease. What are the chances that his daughter develop Huntington? 25%, 50%, 75%, 100% or cannot tell from the information

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter16: Reproductive Technology, Genetic Testing, And Gene Therapy

Section: Chapter Questions

Problem 16QP: A couple has had a child born with neurofibromatosis. They come to your genetic counseling office...

See similar textbooks

Similar questions

A woman who is eight (8) weeks pregnant requests a direct test for Huntington’s disease on her fetus. She tells her geneticist that she wants the test because she recently discovered that there is a family history of the disease in her husband’s family. One of his parents is affected so he is at 50% risk of developing the condition. She is adamant that she does not want to give birth to a baby who is at risk of developing Huntington’s and says that the test will help her to ensure that this is not the case. In counseling, she reveals that she has discussed this issue several times with her husband but he has always said he is not willing to take a test. He does not want to know his status and is extremely anxious about the possibility that he might develop the condition. The woman and her husband are currently separated but are seeing a relationship counselor and trying to work things out. Despite this, the woman says they tend to fight a lot. When it is explained to her in counseling…
The father of three sons and two daughters begins to show symptoms of Huntington disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?
If both parents carry one copy each of the mutation that causes Huntingtons , what are the odds that their child would have the disease ? A)25 B 75 C 50 D 100
The father of three sons and two daughters begins to show symptoms of Huntington's disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?
What would be the phenotypes for each of the following genotypes for Huntington’s Disease? a. Hh = b. hh =
In autosomal dominant disorders, the recurrence risk is ¾(75%) when one affected parent and one carrier parent produce an offspring . True or false
Use these two pictures to answer all the questions completely and correctly.
Neurofibromatosis-1 (NF1) is an autosomal dominant disorder where tumours form in the base layer of the skin or in nerve tissues. What is the probability that individuals II-1 and II-2 will have a genetic son with NF1? Find the image attached.
Huntington disease (HD) is a genetic disorder that usually first appears in middle age and, over time, leads to involuntary movements, impaired speech, difficulty swallowing and speaking, and cognitive decline. There is no cure for HD, and affected individuals eventually die, usually after 10 to 15 years of progressively worsening symptoms. Huntington disease is inherited as an autosomal dominant disorder. Presymptomatic genetic testing for HD is available for people with a family history of the disease. Individuals who have a parent with HD have a 50% chance of inheriting the HD gene and eventually having HD. Some of these individuals want to know if they will eventually get the disease, and they undergo presymptomatic genetic testing. Others do not want to know, given that there is no cure or effective treatment for the disease. If you were at risk for HD, would you want to undergo genetic testing? What are some reasons for and against having a genetic test for HD?
Huntington's disease is characterized by late onset mental deterioration and is invariably fatal. It appears to be caused by an autosomal dominant gene. A man with Huntington's disease (heterozygous) marries a normal woman and they have 5 children. What risk does each child have of contracting the disease? Write the full punnett sqaure equation showing ALL steps used to achieve your answer.
Describe the genetics of Huntington's Disease (choose all that are correct): X-linked Disease-causing alleles are full or partial loss-of-function alleles Autosomal Dominant Rare Late age of onset Recessive
a) Suppose a married couple comes to you for counseling. Both of them have a genetic disorder, but they already have one child who does not have the disorder. They would like to have more children and were told by a friend that since their first child was normal all of their future children would be normal as well. Explain to them the probability of future offspring being normal or having the disease (assume that this is an autosomal disease). Be sure to tell them whether the disease is brought about by a dominant or recessive allele and what fraction of their children (if any) could be carriers for the disease. Explain to the parents the probability of future offspring being normal or having the disease (assume that this is an autosomal disease). Be sure to tell them whether the disease is brought about by a dominant or recessive allele and what fraction of their children (if any) could be carriers for the disease. b) Suppose a different couple has come to see you to…