Biology (MindTap Course List)
Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 8, Problem 3TYU

Before pyruvate enters the citric acid cycle, it is decarboxylated, oxidized, and combined with coenzyme A, forming acetyl CoA, carbon dioxide, and one molecule of (a) NADH (b) FADH2 (c) ATP (d) ADP (e) C6H12O6

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Outline the conditions that direct pyruvate toward the following:(a) Entry into the citric acid cycle(b) Conversion to ethanol and CO2(c) Conversion to lactate(d) Glucose synthesis (gluconeogenesis)In what tissues or organisms is each pathway present?
The two main goals of the citric acid cycle are:   (a) citrate synthesis and gluconeogenesis (b).degradation of acetyl-CoA to produce energy and supply precursors for anabolism (c).degradation of pyruvate to produce energy and supply precursors for anabolism (d).degradation of glucose to produce energy and supply precursors for anabolism (e).degradation of pyruvate to produce energy and synthesize oxaloacetate for gluconeogenesis
Many amino acids are broken down to intermediates of the citric acid cycle. (a) Why can’t these amino acid “remnants” be directly oxidized to CO2 by the citric acid cycle? (b) Explain why amino acids that are broken down to pyruvate can be completely oxidized by the citric acid cycle.

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Biology (MindTap Course List)

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