Biology (MindTap Course List)
11th Edition
ISBN: 9781337392938
Author: Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher: Cengage Learning
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Chapter 8, Problem 4TYU
In the first step of the citric acid cycle, an acetyl group from acetyl CoA reacts with oxaloacetate to form (a) pyruvate (b) citrate (c) NADH (d) ATP (e) CO2
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The two main goals of the citric acid cycle are:
(a) citrate synthesis and gluconeogenesis
(b).degradation of acetyl-CoA to produce energy and supply precursors for anabolism
(c).degradation of pyruvate to produce energy and supply precursors for anabolism
(d).degradation of glucose to produce energy and supply precursors for anabolism
(e).degradation of pyruvate to produce energy and synthesize oxaloacetate for gluconeogenesis
The citric acid cycle converts each acetyl-CoA to [1/2/3/4] molecules of CO2. This pathway is considered [catabolic/anabolic] because it breaks down acetyl-CoA into smaller molecules and [catabolic/anabolic] because the intermediates are building blocks for other metabolites in the cell. The citric acid cycle produces [1/2/3] NADH and [1/2/3] FADH2 for every acetyl-CoA consumed.
help fill in the blanks
In the first step of the citric acid cycle, an acetyl group from acetyl CoA reacts with oxaloacetate to form (a) pyruvate (b) citrate (c) NADH (d) ATP (e) CO2
Chapter 8 Solutions
Biology (MindTap Course List)
Ch. 8.1 - Write a summary reaction for aerobic respiration...Ch. 8.1 - Prob. 1CCh. 8.1 - Prob. 2CCh. 8.2 - Prob. 2LOCh. 8.2 - Prob. 3LOCh. 8.2 - Add up the energy captured (as ATP, NADH, and...Ch. 8.2 - Prob. 5LOCh. 8.2 - Prob. 6LOCh. 8.2 - Prob. 1CCh. 8.2 - Prob. 2C
Ch. 8.2 - What are the roles of NAD+, FAD, and oxygen in...Ch. 8.2 - Prob. 4CCh. 8.3 - Summarize how the products of protein and lipid...Ch. 8.3 - Prob. 1CCh. 8.3 - Prob. 2CCh. 8.3 - Prob. 3CCh. 8.4 - Compare and contrast anaerobic respiration and...Ch. 8.4 - What is the fate of hydrogen atoms removed from...Ch. 8.4 - What accounts for the ATP yield of fermentation...Ch. 8.4 - Is chemiosmosis involved in fermentation? in...Ch. 8 - A chemical process during which a substance gains...Ch. 8 - The reactions of _____ take place within the...Ch. 8 - Before pyruvate enters the citric acid cycle, it...Ch. 8 - In the first step of the citric acid cycle, an...Ch. 8 - Which of the following is the major source of...Ch. 8 - The aerobic part of aerobic cellular respiration...Ch. 8 - Prob. 7TYUCh. 8 - A net profit of only 2 ATPs can be produced...Ch. 8 - When deprived of oxygen, yeast cells obtain energy...Ch. 8 - Which of the following is a correct ranking of...Ch. 8 - Prob. 11TYUCh. 8 - CONNECT Explain why the proton gradient formed...Ch. 8 - CONNECT How are the endergonic reactions of the...Ch. 8 - PREDICT Could the inner mitochondrial membrane...Ch. 8 - Prob. 15TYUCh. 8 - Prob. 16TYUCh. 8 - EVOLUTION LINK The reactions of glycolysis are...Ch. 8 - Prob. 18TYU
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- The citric acid cycle is a critical sequence of reactions for energy production, which take place in the matrix of the mitochondria. The reaction cycle requires materials from the cytosol to be converted into acetyl CoA, which represents the starting point of a new cycle. Which of the following statements about acetyl CoA is true? (a) Acetyl CoA is recycled at the end of every cycle. (b) Oxaloacetate is attached to acetyl CoA to feed the citric acid cycle. (c) Triacylglycerol molecules are transported into the mitochondrial matrix and cleaved by lipases to produce acetyl CoA. (d) Oxaloacetate is converted directly into acetyl CoA to feed the citric acid cyclearrow_forwardOutline the conditions that direct pyruvate toward the following:(a) Entry into the citric acid cycle(b) Conversion to ethanol and CO2(c) Conversion to lactate(d) Glucose synthesis (gluconeogenesis)In what tissues or organisms is each pathway present?arrow_forwardBefore pyruvate enters the citric acid cycle, it is decarboxylated, oxidized, and combined with coenzyme A, forming acetyl CoA, carbon dioxide, and one molecule of (a) NADH (b) FADH2 (c) ATP (d) ADP (e) C6H12O6arrow_forward
- What yield of ATP can be expected from complete oxidation of each of the following substrates by the reactionsof glycolysis, the citric acid cycle, and oxidative phosphorylation?(a) Fructose-1,6-bisphosphate(b) Glucose(c) Phosphoenolpyruvate(d) Glyceraldehyde-3-phosphate(e) NADH(f) Pyruvatearrow_forwardWhich of the following is the second step of Citric Acid Cycle? Select one: a. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH b. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH c. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH d. Malate is oxidized to become oxaloacetate forming NADH e. Fumarate is combined with water to become Malate f. Citrate is rearranged to become Isocitrate g. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide h. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) i. Succinate is oxidized to become fumarate forming FADH2arrow_forwardWhich of the following is the sixth step of Citric Acid Cycle? Select one: a. Succinate is oxidized to become fumarate forming FADH2 b. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH c. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH d. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) e. Malate is oxidized to become oxaloacetate forming NADH f. Fumarate is combined with water to become Malate g. Citrate is rearranged to become Isocitrate h. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide i. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SHarrow_forward
- NAD is reduced in which Citric Acid cycle reaction? (a) Isocitrate to oxaloacetate (b) alpha-ketoglutarate to Succinyl CoA (c) Malate to oxaloacetate (d) Succinate to fumarate (e) Oxaloacetate to Citratearrow_forwardWhich of the following pair of substances are products of the citric acid cycle? a) Acetyl CoA and NADH b) Acetyl CoA and CO2 c) CoA-SH and FADH2 d) Citrate and CO2arrow_forwardWhich of the following statements about the pentose phosphate pathway (PPP) is true? (A) The purpose of the pentose phosphate pathway is to produce NADH for use in anabolic pathways and ribose 6-phosphate for nucleotide synthesis.(B) The oxidative arm of the PPP produces (2) NADPH per glucose 6-phosphate that enters the pathway. (C) Phosphopentose isomerase converts the ribose 5-phosphate made in the oxidative arm of the PPP into ribulose 5-phosphate that is used to form the ribose sugar of nucleotides.(D) The non-oxidative arm of the PPP interconverts between ribose 5-phosphate and a variety of intermediates of b-oxidation. (E) One of the functions of the PPP is to provide NADPH that inhibits glutathione reductase so that it cannot oxidatively damage RBCs.arrow_forward
- What is the net reaction of the citric acid cycle? What happens to each product? OXIDATIVE PHOSPHORYLATION: 3A) Thoroughly explain the biological significance of NADH/H* and FADH₂ and their roles in oxidative phosphorylation. 3B) Describe and diagram the general pathway of the electrons from NADH/H+ and FADH2 to 02 during the electron transport chain. 3C) What is "chemiosmotic coupling", and what is its relationship to ATP synthesis? 3D) During oxidative phosphorylation, what is oxidized and what is phosphorylated?arrow_forward|a) Explain why the citric acid cycle is considered to be the center of cellular metabolism. b) What are the substrates and products corresponding to one turn of the citric acid cycle? (no need for enzymes) c) Which steps of the citric acid cycle release CO2 as a product? Which steps produce NADH or FADH2? Which step produces GTP? d) How much ATP can be generated from glucose when the citric acid cycle is operating?arrow_forwardThe functioning of a particular pathway often depends not only on control enzymes in that pathway but alsoon control enzymes of other pathways. What happens in the following pathways under the indicated conditions? Suggest what otherpathway or pathways might be influenced.(a) High ATP or NADH concentration and the citric acid cycle.(b) High ATP concentration and glycolysis.(c) High NADPH concentration and the pentose phosphate pathway.(d) High fructose-2,6-bisphosphate concentration and gluconeo genesis.arrow_forward
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