Chapter 17.17, Problem 1QQ

Interpretation Introduction

Interpretation:

Amidification process involves what type of reaction has to be chosen from the given options.

Concept Introduction:

Amides are synthesized using amidification reaction.  This involves a reaction between amine and carboxylic acid.  In this reaction, the $-\text{OH}$ group present in carboxylic acid and $-\text{H}$ from ammonia or amine is lost to give amide as the product.  Water is obtained as a by-product in this reaction.  The general reaction scheme for synthesis of amides can be given as,

$\begin{array}{l}\text{Ammonia}\text{+}\text{Carboxylic acid}\stackrel{\text{100 }°\text{C}}{\to }\text{1°}\text{amide}\\ \text{1°}\text{amine}\text{+}\text{Carboxylic acid}\stackrel{\text{100 }°\text{C}}{\to }\text{2°}\text{amide}\\ \text{2°}\text{amine}\text{+}\text{Carboxylic acid}\stackrel{\text{100 }°\text{C}}{\to }\text{3°}\text{amide}\end{array}$