Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 16, Problem 32CTQ
A scientist identifies a potential transcription regulation site 300bp downstream of a gene and hypothesizes that it is a repressor. What experiment (with results) could he perform to support this hypothesis?
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Chapter 16 Solutions
Biology 2e
Ch. 16 - Figure 16.5 In E. coli, the tip operon is on by...Ch. 16 - Figure 16.7 In females, one of the two X...Ch. 16 - Figure 16.13 An increase in phosphorylation levels...Ch. 16 - Control of gene expression in eukaryotic cells...Ch. 16 - Post-translational control refers to: regulation...Ch. 16 - How does the regulation of gene expression support...Ch. 16 - If glucose is absent, but so is lactose, the lac...Ch. 16 - Prokaryotic cells lack a nucleus. Therefore, the...Ch. 16 - The a/a operon is an inducible operon that...Ch. 16 - What are epigenetic modifications? the addition of...
Ch. 16 - Which of the following are true of epigenetic...Ch. 16 - The binding of _____ is required for transcription...Ch. 16 - What will result from the binding of a...Ch. 16 - A scientist compares the promoter regions of two...Ch. 16 - Which of the following are involved in post...Ch. 16 - Binding of an RNA binding protein will the...Ch. 16 - An unprocessed pre-mRNA has the following...Ch. 16 - IS. Alternative splicing has been estimated to...Ch. 16 - Post-translational modifications of proteins can...Ch. 16 - A scientist mutates elF-2 to eliminate its GTP...Ch. 16 - Cancer causing genes are called transformation...Ch. 16 - Targeted therapies are used in patients with a set...Ch. 16 - Name two differences between prokaryotic and...Ch. 16 - Describe how controlling gene expression will...Ch. 16 - Describe how transcription in prokaryotic cells...Ch. 16 - What is the difference between a repressible and...Ch. 16 - In cancer cells, alteration to epigenetic...Ch. 16 - A scientific study demonstrated that rat mothering...Ch. 16 - Some autoimmune diseases show a positive...Ch. 16 - A mutation within the promoter region can alter...Ch. 16 - What could happen if a cell had too much of an...Ch. 16 - A scientist identifies a potential transcription...Ch. 16 - Describe how RBPs can prevent miRNAs from...Ch. 16 - How can external stimuli alter...Ch. 16 - Protein modification can alter gene expression in...Ch. 16 - Alternative forms of a protein can be beneficial...Ch. 16 - Changes in epigenetic modifications alter the...Ch. 16 - A scientist discovers a virus encoding a Protein X...Ch. 16 - New drugs are being developed that decrease DNA...Ch. 16 - How can understanding the gene expression pattern...
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- Put the following processes in order of their occurrence during expression of a eukaryotic gene: a. mRNA processing c. transcription b. translation d. RNA leaves nucleusarrow_forwardWhat are the functions of transcriptional activator proteins and repressor proteins? Explain how they work at the molecular level.arrow_forwardYou are studying the rate of transcription of a particular eukaryotic gene. When the DNA located several thousand bases upstream from the gene is removed, the transcription rate of the gene decreases dramatically. How would you interpret these results?arrow_forward
- At 2:00 pm, you measured intracellular arginine at 100M. After addition of 200M of arginine to the cell, you, at 2:45 pm, measured intracellular arginine levels to be still at 100M. The most likely explanation is: Arginine bound to the active site of the repressor protein Arginine bound to the allosteric site of RNA polymerase Arginine was in excess in the cell and acted as an inducer Arginine was in excess in the cell and bound to the operator Arginine bound to the allosteric site of the repressor proteinarrow_forwardWhat role does an operator sequence serve in bacterial gene expression regulation? Describe one change in bacterial cells that can cause a repressor protein to go from inactive to active or from active to inactive.arrow_forwardYou are a genetic engineer that is working on transcriptional regulation in living organisms. In addition to your day job, you are a video game connoisseur and are designing a cell phone game where participants design the features of an organism that is the best at up-regulating transcription of a gene, WINNING. Participants are able to pick from a variety of organisms, cis regions, trans factors and a variety of enzymes. You want to set the high score on the leader board so you play the game and design the following features into your organism. - You need to describe ALL the features you will be including into your organism as well as what organism you picked for your entry. You need to include all the components of transcription, key features of transcriptional regulation and other features that will increase transcription to the highest level. You need to explain why you included every feature and how each will contribute to increased gene expression. Be creative and error on the…arrow_forward
- Briefly describe the significance of regulatory factors in transcription process. Why the promoter is called an essential regulatory element.arrow_forwardYou are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate this complex process, you decide to draw for the class a typical eukaryotic gene/transcription unit with its major regions, such as the promoter regions, where the RNA polymerase II and transcription factors would bind From the list given - choose all components that you think are part of a typical eukaryotic gene From the list given - choose all the regulatory sequences that you think would control the expression of this eukaryotic gene From the list given - choose all of the regulatory proteins that would bind the eukaryotic gene to control its expressionarrow_forwardGive only typing answer with explanation and conclusionarrow_forward
- Which of the following statements is false? a mutation in a 5' or 3' splice site must alter the sequence of the protein encoded by a gene a mutation in a transcriptional terminator is unlikely to alter the sequence of a protein encoded by a gene. a mutation in a promoter is unlikely to alter the sequence of the polypeptide encoded by a gene a missense mutations replaces one amino acid with a different amino acid a frameshift mutation changes the sequence of a protein 000 0arrow_forwardA KDEL sequence is a sequence of amino acids in a protein that binds a KDEL receptor, which helps recycle it back to the ER. Name two techniques a scientist could use in combination to experimentally demonstrate the function of a KDEL sequence. (To help you think about how to answer this: What would happen if the KDEL sequence were nonfunctional? How could you observe the result?) Please answer this and thank you!arrow_forwardWhat is a major difference between activator proteins and repressor proteinsarrow_forward
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