Chapter 13, Problem 13.104EP

Interpretation Introduction

Interpretation: To determine the number of molecules of NADPH that is produced per $\text{glucose 6}-\text{phosphate}$ in the pentose phosphate pathway.

Concept introduction: The pentose phosphate pathway is defined as the metabolic pathway in which NADPH, $\text{ribose 5}-\text{phosphate}$, and other sugar phosphates are produced from $\text{glucose 6}-\text{phosphate}$.

Pentose phosphate pathway is a two-stage metabolic pathway. The first stage of phosphate pentose pathway is the oxidative stage and the second stage is a non-oxidative stage.

Nicotinamide adenine dinucleotide phosphate is associated with the redox reactions in metabolism. Its reduced form is NADPH and oxidized form is ${\text{NADP}}^{+}$. Structurally, ${\text{NADP}}^{+}/\text{NADPH}$  is the phosphorylated version of ${\text{NAD}}^{+}/\text{NADH}$.