The ∆G°’ for hydrolysis of phosphoenol pyruvate is -62.2 kJ/mol. The standard freeenergy of ATP hydrolysis is -30.5 kJ/mol. A. What is the standard free energy and K eq of the spontaneous reaction betweenADP/ATP and phosphoenol pyruvate. B. Repeat A for F-1,6-BP (∆G°’=-16.7 kJ/mol) and 1,3-BPG (∆G°’=-49.6 kJ/mol)hydrolysis. C. If the ATP and ADP concentrations are 8mM and 1mM respectively, what would bethe ratio of pyruvate/phosphoenolpyruvate at equilibrium?

Biochemistry
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Chapter26: Synthesis And Degradation Of Nucleotides
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The ∆G°’ for hydrolysis of phosphoenol pyruvate is -62.2 kJ/mol. The standard free
energy of ATP hydrolysis is -30.5 kJ/mol.


A. What is the standard free energy and K eq of the spontaneous reaction between
ADP/ATP and phosphoenol pyruvate.


B. Repeat A for F-1,6-BP (∆G°’=-16.7 kJ/mol) and 1,3-BPG (∆G°’=-49.6 kJ/mol)
hydrolysis.


C. If the ATP and ADP concentrations are 8mM and 1mM respectively, what would be
the ratio of pyruvate/phosphoenolpyruvate at equilibrium?

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