Table 1. normal protein 1 2 Frameshift mutation worksheet 3.5 DNA 3' ATTGTGTACTAAAAGCATTTTACAGACTGAAGGTTG RNA 5' UAACACAUGAUUUUCGUAAAAUGUCUGACUUCCAAC protein Table 2. deletion at position #2 No Start codon MET ILE PHE VAL LYS CYS LEU SER THR ASN 35 RNA 5' VAAACAUGAVNUUCGUÅÅAAVGUCUGACVUCCAAC protein Table 3. addition at position #5 1 3 5 ASNVI insertion LEURI RNA 5' VAACA.CAVGAVUUUCGUAAAAAVGUCUGACUUCCAAC protein Table 4. deletion at position #3 1 METILE PHEVALLYS MET SE RASP PHF GLN 5 RNA 5' VAACACAUGAVUVUCGUAAAUGUCUGACUUCCAAC protein Table 5. three deletions HISMETILEPHEVALASNVAL 1 2 3 RNA 5' VAACACAUGAVUUUCGUAAAGUCGACUUCCAAC protein METILEPHEVALLYSSERTHRSERASN Frameshift mutation worksheet (continued) CTCTTCACTAATTCGGGCGGATTTCCCGAAAAAAA GAGAAGUGAUUAAGCCCGCCUAAAGGGCUUUUUUU GLU LYS 5' DNA 3' RNA protein 3' RNA protein 3' RNA protein 3' RNA protein 3' RNA protein

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter29: Transcription And The Regulation Of Gene Expression
Section: Chapter Questions
Problem 1P
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Based on the first paper with the tables, fill out the second worksheet.

Table 1. normal protein
1
2
Frameshift mutation worksheet
3.5
DNA 3' ATTGTGTACTAAAAGCATTTTACAGACTGAAGGTTG
RNA 5' UAACACAUGAUUUUCGUAAAAUGUCUGACUUCCAAC
protein
Table 2. deletion at position #2
No Start codon
MET ILE
PHE VAL LYS
CYS
LEU
SER
THR
ASN
35
RNA 5' VAAACAUGAVNUUCGUÅÅAAVGUCUGACVUCCAAC
protein
Table 3. addition at position #5
1
3 5
ASNVI
insertion
LEURI
RNA 5' VAACA.CAVGAVUUUCGUAAAAAVGUCUGACUUCCAAC
protein
Table 4. deletion at position #3
1
METILE PHEVALLYS MET SE RASP PHF GLN
5
RNA 5' VAACACAUGAVUVUCGUAAAUGUCUGACUUCCAAC
protein
Table 5. three deletions
HISMETILEPHEVALASNVAL
1
2
3
RNA 5' VAACACAUGAVUUUCGUAAAGUCGACUUCCAAC
protein
METILEPHEVALLYSSERTHRSERASN
Transcribed Image Text:Table 1. normal protein 1 2 Frameshift mutation worksheet 3.5 DNA 3' ATTGTGTACTAAAAGCATTTTACAGACTGAAGGTTG RNA 5' UAACACAUGAUUUUCGUAAAAUGUCUGACUUCCAAC protein Table 2. deletion at position #2 No Start codon MET ILE PHE VAL LYS CYS LEU SER THR ASN 35 RNA 5' VAAACAUGAVNUUCGUÅÅAAVGUCUGACVUCCAAC protein Table 3. addition at position #5 1 3 5 ASNVI insertion LEURI RNA 5' VAACA.CAVGAVUUUCGUAAAAAVGUCUGACUUCCAAC protein Table 4. deletion at position #3 1 METILE PHEVALLYS MET SE RASP PHF GLN 5 RNA 5' VAACACAUGAVUVUCGUAAAUGUCUGACUUCCAAC protein Table 5. three deletions HISMETILEPHEVALASNVAL 1 2 3 RNA 5' VAACACAUGAVUUUCGUAAAGUCGACUUCCAAC protein METILEPHEVALLYSSERTHRSERASN
Frameshift mutation worksheet (continued)
CTCTTCACTAATTCGGGCGGATTTCCCGAAAAAAA
GAGAAGUGAUUAAGCCCGCCUAAAGGGCUUUUUUU
GLU LYS
5' DNA
3' RNA
protein
3' RNA
protein
3' RNA
protein
3' RNA
protein
3' RNA
protein
Transcribed Image Text:Frameshift mutation worksheet (continued) CTCTTCACTAATTCGGGCGGATTTCCCGAAAAAAA GAGAAGUGAUUAAGCCCGCCUAAAGGGCUUUUUUU GLU LYS 5' DNA 3' RNA protein 3' RNA protein 3' RNA protein 3' RNA protein 3' RNA protein
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