You are working on a newly described transcription factor that appears to have an important role in the differentiation of embryonic stem cells into neural lineage. Deleting your transcription factor is resulting in upregulation of some genes and downregulation of some genes. a. Speculate 2 mechanisms by which your transcription factor is responsible for the regulation of both these set of genes. b. Describe a combination of 2 different techniques you will utilize to distinguish direct targets versus indirect targets.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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You are working on a newly described transcription
factor that appears to have an important role in the
differentiation of embryonic stem cells into neural
lineage. Deleting your transcription factor is resulting
in upregulation of some genes and downregulation
of some genes.
a. Speculate 2 mechanisms by which your
transcription factor is responsible for the regulation
of both these set of genes.
b. Describe a combination of 2 different techniques
you will utilize to distinguish direct targets versus
indirect targets.
Transcribed Image Text:You are working on a newly described transcription factor that appears to have an important role in the differentiation of embryonic stem cells into neural lineage. Deleting your transcription factor is resulting in upregulation of some genes and downregulation of some genes. a. Speculate 2 mechanisms by which your transcription factor is responsible for the regulation of both these set of genes. b. Describe a combination of 2 different techniques you will utilize to distinguish direct targets versus indirect targets.
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