For each pedigree below: 1) determine the mode of inheritance; and 2) label any individuals that are known to be heterozygous or hemizygous dominant. a. I IT III 2 3 6 C. I II III IV 1 2 3 5 3 3 4 ге + 27. 28. For Pedigree a, what is the probability that if II 3 has another child with his wife that the child will be affected? Show your work. For Pedigree c, what is the probability that if III 2 were to marry III 3 that their first child would be an affected female? An affected male? Show your work.
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- 6) For the pedigree shown below, answer the following questions. I II III a) What type of inheritance is shown? Explain how you know. b) The genotype of individual I -2 is The genotype of individual II -1 isPlease answer both questions in detail. Correct answers are highlighted.The pedigree shows a family in which several members have suffered from one and the same disease (look at the picture to be able to answer) a) Is it a dominant or recessive allele that causes the disease? Motivate your answer. b) Is allele autosomal or sex-linked? Motivate your answer. c) What is the probability that III-3 and III-4 will have a healthy child? Motivate your answer.
- Please consider the following pedigree. Assume that people who marry in to the family do not carry the allele unless otherwise indicated. Assume complete penetrance. I II 5 6 III 6 IV 1 2 a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR) (ii) an autosomal dominant allele (AD) (iii) a X-linked recessive allele (XR) (iv) a X-linked dominant allele (XD) b. Provide a genotype for individual III-6 for the most likely mode of inheritance as determined in (a).Please consider the following pedigree. Assume that people who marry in to the family do not carry the allele. Assume complete penetrance. I II III 3 IV 1 2 a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR) (ii) an autosomal dominant allele (AD) (iii) a X-linked recessive allele (XR) (iv) a X-linked dominant allele (XD) b. Based strictly on the characteristic patterns of inheritance that define the four different options in (a), give a definitive motivation for the most likely mode of inhertance.The following pedigree illustrates the inheritance of Duchenne Muscular Dystrophy, a condition characterized by progressive weakness and degeneration of skeletal muscles due to absence of dystrophin. 2.
- The pedigree below shows the phenotypes of the ABO blood groups and Rhesus factors [positive (+) and negative (-)] for several members of a family. I (B+ AB- 1 2 3 4 II O- A+ В- B- AB+ A+ 1 2 4 5 6 a. What are the ABO blood group genotypes of individuals I-1 and I-2? b. Which child/ren of individual I-4 can donate blood to him? c. Which individual in the pedigree can donate blood to all the other individuals in the pedigree?Please consider the pedigree below. There are no cases of false paternity. The ABO blood group phenotypes of individuals who marry into the family are a true reflection of their ABO genotypes. image attached I a. Which individual/s definitely has/have Bombay phenotype in the descendants of I-1 and I-2? b. What are the genotypes of individuals I-1 and II-2 at the ABO and H loci?Please consider the pedigree below. There are no cases of false paternity. I B II A 2 3 III AB (A IV в 1 a. Which individual/s definitely has/have Bombay phenotype in the descendants of I-1 and I-2? b. What are the genotypes of individuals II-2 and III-2 at the ABO and H loci?
- Using the pedigree chart, explain: a) The number of generations seen. b) If all blue-coloured shapes are affected with disease X- how many males are affected? how many females are affected? c) Does this disease have a dominant or recessive inheritance pattern? Justify your answer.Cystic Fibrosis (CF) is an autosomal recessive condition. Therefore, heterozygous (Cc) carriers do not display symptoms. Two parents who are carriers plan to start a family and you are a genetic counselor helping to advise them about their chances of having children affected by CF. a) Suppose the couple has 4 children, each one year apart. What is the probability that all 4 children will inherit CF? b) What is the probability that any 3 of their 4 children will not inherit CF, but 1 will be affected? c) What is the probability that their first child will not inherit CF, but the younger 3 children will inherit CF?*Cystic fibrosis is a rare autosomal recessive condition. phenotypically normal man whose father had cystic fibrosis marries a phenotypically normal woman from outside the family.² a) Draw the pedigree as far as described. b) If the frequency of heterozygotes in the general population is 1/50, what is the probability that the couple's first child will have cystic fibrosis? c) If the first child does have cystic fibrosis, what is the probability that the second child will be normal?