**9. Make a pedigree for each of the following situations. For each individual, write the individual's genotype (when possible) next to the individual's symbol (e.g., ☐ XᵃY, ■ Gg):****a.** Two parents do not have cystic fibrosis and they have a daughter with cystic fibrosis and a son who does not have cystic fibrosis. The daughter grows up and she mates with a male who does not have cystic fibrosis. Their only child is a boy and he has cystic fibrosis.**b.** A man with hemophilia mates with a female without hemophilia. They have one son and one daughter. The daughter has hemophilia and the son does not have hemophilia. The son grows up, and he marries and mates with a female. Their only child is a boy, and he has hemophilia.

Name: **9. Make a pedigree for each of the following situations. For each i
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Description: **9. Make a pedigree for each of the following situations. For each individual, write the individual's genotype (when possible) next to the individual's symbol (e.g., ☐ XᵃY, ■ Gg):****a.** Two parents do not have cystic fibrosis and they have a daug

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Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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**9. Make a pedigree for each of the following situations. For each individual, write the individual's genotype (when possible) next to the individual's symbol (e.g., ☐ XᵃY, ■ Gg):**

**a.** Two parents do not have cystic fibrosis and they have a daughter with cystic fibrosis and a son who does not have cystic fibrosis. The daughter grows up and she mates with a male who does not have cystic fibrosis. Their only child is a boy and he has cystic fibrosis.

**b.** A man with hemophilia mates with a female without hemophilia. They have one son and one daughter. The daughter has hemophilia and the son does not have hemophilia. The son grows up, and he marries and mates with a female. Their only child is a boy, and he has hemophilia.

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The cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation causes this hereditary disease. The CFTR gene gives the CFTR protein instructions. The CFTR protein controls the movement of salt and fluids into and out of cells throughout the body. The transmembrane conductance regulator in cystic fibrosis distributes chloride ions across epithelial cell membranes properly. The CFTR gene mutation or malfunction causes cystic fibrosis. Cystic fibrosis is caused by a defective gene that impairs ion transport. The increased salt content in the sweat gland is one of the symptoms.
Secretions in the lungs, pancreas, liver, gut, and reproductive organs are thick and viscous.

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