You coat microfilaments with the myosin S1 fragment and add these coated microfilaments to the slide with Protein Y stuck on a slide. You observe the coated microfilaments move, and they move in the direction with the barbed ends leading. Your advisor is ecstatic with this observation, telling you that you have made a major discovery. What is novel about this discovery? ng. Microfilament movement Protein Y

At which stage of development does the Id protein function? Why is its function important?

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Marfan syndrome is due to a mutation in a gene that encodes aprotein called fibrillin-1. It is inherited as a dominant trait. Thefibrillin-1 protein is the main constituent of extracellular microfibrils.These microfibrils can exist as individual fibers or associatewith a protein called elastin to form elastic fibers. People with thedisorder tend to be unusually tall with long limbs, and they mayhave defects in their heart valves and aorta. Let’s suppose aphenotypically unaffected woman has a child with a man whohas Marfan syndrome.A. What is the probability this child will have the disease?B. If this couple has three children, what is the probability thatnone of them will have Marfan syndrome?

Mutations to SRP72 (the RNA component of the signal recognition particle) are known to cause some forms of familial bone marrow failure. Which of the following protein(s) is/are potentially affected by such deleterious mutations? Choose all that apply Epidermal growth factor receptor (EGFR) Cytochrome c Insulin (a secreted protein) uS7 (a small ribosamal subunit protein from all dornains of life) DO00

The BMP-Nodal gradient so vital to amphibian and fish development may be critically important in other vertebrates (including humans) as well. Moreover, can any field of pluripotent cells (such as human embryonic stem cells)respond to gradients of BMP and Nodal signals?

Hurler syndrome is due to a mutation in a gene that encodes aprotein called α-l-iduronidase. This protein functions withinlysosomes as an enzyme that breaks down mucopolysaccharides(a type of polysaccharide that has many acidic groups attached).When this enzyme is defective, excessive amounts of the mucopolysaccharides dermatan sulfate and heparin sulfate accumulatewithin the lysosomes, especially in liver cells and connectivetissue cells. This accumulation leads to symptoms such as anenlarged liver and spleen, bone abnormalities, corneal clouding,heart problems, and severe neurological problems. The pedigreebelow contains three members affected with Hurler syndrome,indicated with black symbols. Based on this pedigree, does thissyndrome appear to follow autosomal recessive, autosomaldominant, X-linked recessive, or X-linked dominant inheritance?Explain your reasoning.

How do the Arp2/3 complex and NPFs nucleate the assembly of actin filaments?

Dr. William's lab is studying cell division on a mutant primary mouse cell line. Interestingly the drug, Colchicine has no effect on any types of tubulin subunits expressed by the cell line. Which of the following conditions/s will arrest the cell line’s cell division during mitosis? Group of answer choices (B) and (C) are correct (A) and (C) are correct (A) High concentration of Colchicine (B) Low concentration of Colchicine (C) Taxol

The human Myoglobin gene is expressed in cardiomyocyte cells but not in hepatocyte cells because The Myoglobin gene is in cardiomyocyte cells but not in hepatocyte cells Different transcriptional regulatory proteins are present in cardiomyocyte and hepatocyte cells The RNA Polymerase Il complex is present in cardiomyocyte cells but not in hepatocyte cells The Myoglobin gene is packed in heterochromatin in cardiomyocyte cells and euchromatin in hepatocyte cells Different promoters are present in cardiomyocyte and hepatocyte cells