OH H₂N ethanolamine ammonia lyase Vitamin B12 + NH3 H

Elevated blood plasma levels of alkaline phosphatase (hyperphosphatasaemia) are an indication of a number of pathologies. Briefly comment on the use of alkaline phosphatase assays as a diagnostic aid for a single common medical condition.  (word limit 120 words including citations and references.

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Should teenagers be prescribed statins if they are diagnosed with hypercholesterolemia? Why or why not?

explain the phenylketonuria disease mechanism

Is there a better solution for treating hypercholesterolemia that statins

Explain why the hexose monophosphate shunt is so important.

Why is D-glucose (dextrose), given intravenously to patients rather than sucrose?

. Suggest the effects of each of the following mutations on the physio- logical role of chymotrypsinogen: (a) R15S (b) Cis (c) T147S

The plasma profiles of codeine (COD) and metabolites for 2 individuals (labeled A and B) are shown below. The X-axis is time in hours after an oral dose of codeine. [M=morphine; C6G=COD-6-glucuronide; M3G = morphine-3-glucuronide; NM (ignore)]. Note the data is shown on a log scale on the Y-axis. (A) Which individual is the poor metabolizer? Explain how you know this from the profiles? (B) Is this a problem for cough suppression? Explain. -CH HO Codeine COD 10 000 1000 C6G COD 100 M3G M6G NM 10 M 10 20 30 0 10 20 30 Plasma concentration (nmol I-)