mutation 5' 1 3' 5' 3' 5' 3' 4 Mutations in splice sites can lead to the formation of abnormal proteins. The diagram illustrates a mutation in the 3' splice site between exons 1 and 2 which prev SNRNPS to that site. Which of the following consequences could be a result of this mutation? 1. The mutant mRNA contains intronic sequences. 2. The mutant mRNA is shorter compared to wild-type (original) MRNA. 3. The mutant MRNA produces a longer protein compared to wild-type (original) MRNA. 4. The mutant mRNA has exon 2 deleted. O A. 1, 2 and 3 O B. 1 and 3 O C. 2 and4 O D. 4 only O E. All of 1, 2, 3 and 4 are correct

Human Anatomy & Physiology (11th Edition)
11th Edition
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Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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mutation
5'
1
3'
5'
3'
5'
3'
4
3
Mutations in splice sites can lead to the formation of abnormal proteins. The diagram illustrates a mutation in the 3' splice site between exons 1 and 2 which prevents binding of
snRNPs to that site.
Which of the following consequences could be a result of this mutation?
1. The mutant mRNA contains intronic sequences.
2. The mutant MRNA is shorter compared to wild-type (original) MRNA.
3. The mutant MRNA produces a longer protein compared to wild-type (original) MRNA.
4. The mutant MRNA has exon 2 deleted.
O A. 1, 2 and 3
O B. 1 and 3
O C. 2 and 4
D. 4 only
O E. All of 1, 2, 3 and 4 are correct
Transcribed Image Text:mutation 5' 1 3' 5' 3' 5' 3' 4 3 Mutations in splice sites can lead to the formation of abnormal proteins. The diagram illustrates a mutation in the 3' splice site between exons 1 and 2 which prevents binding of snRNPs to that site. Which of the following consequences could be a result of this mutation? 1. The mutant mRNA contains intronic sequences. 2. The mutant MRNA is shorter compared to wild-type (original) MRNA. 3. The mutant MRNA produces a longer protein compared to wild-type (original) MRNA. 4. The mutant MRNA has exon 2 deleted. O A. 1, 2 and 3 O B. 1 and 3 O C. 2 and 4 D. 4 only O E. All of 1, 2, 3 and 4 are correct
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