Metabolic syndrome is a clustering of various conditions including high blood pressure, high blood sugar, excess body fat, high serum triglycerides, and low high-density lipoproteins. Scientists studying metabolic syndrome cultured fibroblast cells from a metabolic syndrome patient and a healthy volunteer and challenged the cells to 100 nM insulin. Ten minutes after the stimulus was applied, they used a protein immunoblot to measure the amount of phosphorylated insulin receptor in the cultures. Use the passage to answer the question. The level of insulin in the blood is regulated by negative feedback. Which observation MOST supports this model? A. Insulin secretion increases metabolic syndrome symptoms. B. Insulin secretion decreases metabolic syndrome symptoms. C. Insulin receptor phosphorylation increases insulin secretion. D. Insulin receptor phosphorylation decreases insulin secretion.
Use the passage to answer the question.
The level of insulin in the blood is regulated by negative feedback. Which observation MOST supports this model?
-
A.
Insulin secretion increases metabolic syndrome symptoms.
-
B.
Insulin secretion decreases metabolic syndrome symptoms.
-
C.
Insulin receptor phosphorylation increases insulin secretion.
-
D.
Insulin receptor phosphorylation decreases insulin secretion.
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Insulin Receptor
Phosphorylated
Insulin Receptor
Healthy
0
Metabolic
Syndrome
100
100 0"
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