Dr. Ryan, Dr. Shapiro, and Dr. Lakey are pioneers in an islet transplant program at the University of Alberta in Edmonton.   The Edmonton Protocol is a transplant procedure developed by them where donor islet cells are transplanted into the pancreas of Type 1 diabetic patients in combination with a glucocorticoid free immunosuppressive regimen. One year after transplant, none of the patients had returned to requiring insulin injections. Select the FOUR statements below that describe a patient who does not require insulin injections (insulin independent). Beta cells secrete insulin in response to increased blood glucose levels. Beta cells secrete insulin in response to decreased blood glucose levels. Urine samples indicate high levels of glucose. Urine samples indicate no glucose. Muscle, liver cells, and adipose tissue are permeable to glucose. Muscle, liver, cells and adipose tissue are impermeable to glucose. Water excretion is normal. Extra water is excreted.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Dr. Ryan, Dr. Shapiro, and Dr. Lakey are pioneers in an islet transplant program at the University of Alberta in Edmonton.   The Edmonton Protocol is a transplant procedure developed by them where donor islet cells are transplanted into the pancreas of Type 1 diabetic patients in combination with a glucocorticoid free immunosuppressive regimen. One year after transplant, none of the patients had returned to requiring insulin injections.

Select the FOUR statements below that describe a patient who does not require insulin injections (insulin independent).

  1. Beta cells secrete insulin in response to increased blood glucose levels.
  2. Beta cells secrete insulin in response to decreased blood glucose levels.
  3. Urine samples indicate high levels of glucose.
  4. Urine samples indicate no glucose.
  5. Muscle, liver cells, and adipose tissue are permeable to glucose.
  6. Muscle, liver, cells and adipose tissue are impermeable to glucose.
  7. Water excretion is normal.
  8. Extra water is excreted.
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