The data below depicts the tissue-specificity for mRNA expression of the RAG1 gene in various human tissues. Which of the following are mechanisms that could account for the RAG1 gene being expressed the thymus, but not other tissues (select all that apply)?
The data below depicts the tissue-specificity for mRNA expression of the RAG1 gene in various human tissues. Which of the following are mechanisms that could account for the RAG1 gene being expressed the thymus, but not other tissues (select all that apply)?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The data below depicts the tissue-specificity for mRNA expression of the RAG1 gene in various human tissues. Which of the following are mechanisms that could account for the RAG1 gene being expressed the thymus, but not other tissues (select all that apply)?
Transcribed Image Text:Kidney. 1
Tonsil.1
Lymphnode.1-
Thymus. 1-
Bonemarrow. 1 9.65
Adrenalgland. 1-
AdrenalCortex. 1-
OlfactoryBulb.1
Tráches.1
Salivarygland. 1
Pituitary. 1
Fetalliver. 1
Fetallung.1
Fetal Thyroid. 1
Uterus. 1
Adipocyte. 1
Pancreaticlslet. 1
Pancreas. 1
Testis SeminiferousTubule.1
TestisLeydigCell.1
TestisIntersitial.1
Testis GermCell.1
Testis. 1
Colorectaladenocarcinoma.1
BronchialEpithelialCells. 1
SmoothMuscle. 1
CardiacMyocytes. 1
Leukemialymphoblastic(MOLT-4).1
Leukemis_chronicMyelogenousk-582.1
Lymphoma_burkitts (Daudi). 1
Leukemis_promyelocytic-HL-60.1
Lymphoms burkitts(Raji). 1
Thyroid. 1
Prostate. 1
Lung.1
Placenta. 1
CD71+ EarlyErythroid. 1
Small intestine. 1
Colon.1
Liver. 1
Heart. 1
250
500
14.70+/-1.20
750
1.00e+3
1032
A. Transcription of RAG1 is regulated by a transcription activator only expressed in the thymus
B. The DNA sequence for RAG1 is only found in thymus
C. An enzyme that modifies histones at the RAG1 promoter is only found in the thymus
D. The transcripton factors that activates RAG1 is activated by a hormone only found in the thymus
E. The transcription factor that regulates RAG1 is sequestered in the cytoplasm in all cell types expcept the thymus
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