Consider the graph below. Reaction rate (v) Vmax 0 Effector 3 mM Effector 1, mM Control 0 mM Ko.5 (3) Kos (1) Ko.5 (0) [S]
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- Question 28 A client has to receive intravenous fluid 5% dextrose 1500 ml in 24 hours. Calculate the quantity of fluid to be given in 1 hour in ml. Show the steps of Calculation For the toolbar, press ALT+F10 (PC) or ALT+FN+F10 (Mac). BIUS Paragraph Arial 14pxQuestion 17 You have pethidine injection 100 mg in 2 mL. The patient is prescribed 75 mg. How much do you draw up?QUESTION 38 In a 250µl reaction containing 0.3 nmol of a Michaelis enzyme with Km = 4.4 x 10 M and saturating substrate concentration, product was formed at an initial velocity of 6.3 x 10 M min-1. What is kcat for this enzyme? Give your answer in 3 sigfigs in scientific notation, for example 1.20 e -3 Click Save and Submit to save and submit. Click Save All Answers to save all answers. O Type here to search 78°F Mostly cloudy End 4) DII PrtScn F8 Home F9 F6 F2 F3 F4 *- & 7 8. 4. #3
- QUESTION 23 Digoxin, a toxin derived from the foxglove (shown), can be used to treat heart disorders such as atrial fibrillation. Digoxin's mechanism of action is to inhibit the Nat/K* ATPase. Which of the following is the most likely side effect of Digoxin treatment? Failure to transport glucose into cells during an extended fast Failure to transport glucose into cells after after eating a large meal Enhanced response of muscle cells to Acetylcholine Failure to transport Cl out of the cell using direct active transport 0000Question 16 For a Michaelis Menten reaction the following rate constants were observed: k1 = 7x 107/M-sec k1 =1x 103/sec k2 = 2 x 104/sec The value of Km is: Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a 0.3 M b 0.03 M 0.003 M d. 0.0003M e 0.00003 M f 0.000003 M 0.0001 M 0.01 M i 0.001MQuestion 20 The client with inflammatory bowel disease has the following blood test results. Identify the correct interpretation: Patient Normal Range CRP (C-Reactive Protein) 10 ≤5.0 mg/L Hgb (hemoglobin): 104 (130 - 180 g/L (Male); (115 - 165 g/L (Female)) HCT (hematocrit): 0.35 (0.400 - 0.540 L/L (Male)) (0.370 - 0.470 L/L (Female)) Platelets: 350 (150 - 400 x 109/L) Question 20 options: Inflammation Hypoalbuminemia Infection Dehydration
- QUESTION 35 Calculate the reaction rate of catalase at room temperature using the following data. Depth of Hydrogen Peroxide Solution Time = 66.3 seconds 2.2 cm O 3.000 68.50 0.080 O 30.140 O 0.033Question: A sample of 5 mL of blood is tested for the enzyme creatine kinase (CK). The blood test reveals that the sample contains a total amount of 1.050 IU of CK. The normal range for CK in a blood test is 25-200 IU per liter. The patient from whom this blood was drawn then has creatine kinase levels that areQuestion:- The enzyme aromatase is found in the cytoplasm of some cells and converts testosterone to estrogen. You decide to test aromatase from a particular cell, and oops, your lab partner admits he drastically increased the pH in all the test tubes. Which of the following is a likely result? a. The enzyme will be denatured and the substrate will not bind to the active site. b. The enzyme will convert testosterone to estrogen at a faster rate. c. The mistake will have no effect on the experiment, because enzymes are not sensitive to pH. d. The free energy will be lowered and the reaction will not proceed spontaneously.
- Question 33 Orciprenaline (C₁₁H₁7NO3, 211.258 g/mol) is a bronchodilator used in the treatment of asthma. The BP assay for orciprenaline tablets is described below. HO The following information was obtained during the assay: Weight of 20 tablets = 2.5564 g Weight of tablet powder assayed = 0.5266 g Absorbance reading - 0.5868 Stated content per tablet = 20 mg A (1%, 1 cm) at 276 nm = 72.3 OH H N OH "Weigh and powder 20 tablets. Shake a quantity of the powder containing 80 mg of orciprenaline sulphate with 50 mL of 0.01 M hydrochloric acid (HCI), filter and add sufficient 0.01 M HCI to the filtrate to produce 100 mL. Dilute 10 mL to 100 mL with 0.01 M HCI and measure the absorbance of the resulting solution at the maximum at 276 nm." Orciprenaline 4 Answer the following questions, explaining your reasoning clearly. a) Calculate the amount of orciprenaline in the tablet powder analyzed. b) Calculate the average amount of orciprenaline per tablet. c) Calculate the percentage of the stated…QUESTION 2 CH3COO-C₂H5 + H₂O → CH3COOH + C₂H5OH Ethyl acetate Acetate Ethanol Ethyl acetate, acetate and ethanol were added to water solution in concentrations of 0.3M and left at 25°C until the solution reached an equilibrium state: ethyl acetate = 0.276 M; acetate=0.012 M; ethanol = 0.012 M; The experiment was repeated at the same temperature with the initial concentration of 0.1M of ethyl acetate. What will be the concentration of ethyl acetate (in moles/liter) be once equilibrium is achieved?Question 1. Enzymes, proteins and deoxyribonucleic acid (DNA) are important biological macromolecules. Enzymes are not only speed up the reaction, but also are necessary for DNA reproduction. e) Michaelis - Menten Kinetics model explains how reaction rates are depending on the concentration of enzyme and substrate. i. What is meant by the saturation of enzyme? ii. A decrement in enzyme activity is known as enzyme inhibition. Based on normal enzyme activity, explain the enzyme kinetics for competitive inhibition and noncompetitive inhibition, as shown in Figure 1. Normal enzyme Competitive inhibitor Noncompetitive inhibitor Substrate concentration Figure 1: Enzyme inhibition f) What is the importance of cofactor in the enzyme activity? Give an example of a disease that is related with cofactors. Rate of reaction