In order to optimize acetylcholinesterase inhibition, a set of benzylamine derivatives were studied,and the following relationship was found:log== -0.187 n + 0.57o + 3.893 (b). Based on the expected change in 7, how would you expect the activity of compound C tocompare to Compound A?C

The given relationship [log(1/C) = -0.187π + 0.57σ + 3.893] represent Hansch QSAR analysis model.…

Answered: In order to optimize…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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In order to optimize acetylcholinesterase inhibition, a set of benzylamine derivatives were studied, and the following relationship was found: log) = -0.187 n+ 0.57o + 3.893