What is the Nernstian slope in potentiometric analysis of Ca2+ when Ecell (mV) is plotted against pSr? +29.6 mV per ionic unit -29.6 mV per ionic unit -59.2 mV per ionic unit +59.2 mV per ionic unit
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- A Br selective electrode is applied for measuring bromide ions in saline solution. Cl' ions were found to interfere, with a kPot = 0.0050. %3D After calibration, the ISE equation was determined to be y = -70 mV - 59.2mV*log(x). If we measure a potential of 93 mV, and the [CI]=0.100 M, what was the [Br'] in units of M? O 0.00821 O 0.100 O 0.0050 O 0.123 O Correct answer not found in other optionsConsider a suspension of particles (isoelectric point is at pH 6) in water at pH 2 and a NaCl concentration of 0.001 M. Describe how the strength of repulsion varies with the following changes, assuming all other conditions remain constant. Give a description (more than just increase or decrease) in terms of the effect on the double layer thickness and the zeta potential. (a) Change from 0.001 M NaCl to 0.1 M NaCl, (b) Change from pH = 2 to pH = 5.Consider the following release data for a drug in water Q (Cumulative amount released in mg/cm?) Time (min) 15 12 30 16 45 20 60 23 120 32 240 46 480 65 1. On MS Excel , Plot Q Vs t, and Q Vs vt in separate graphs. Determine the equation and R2 for each curve. solve Q2 only show me by steps 2. Based on the R for the graphs, which release pattern does the drug follow, and why?
- Example The standard half electrode potential for Fe²+ vs SHE is 0.77 V. What is the value of Ee at T = 298K when: [Fe³+] = 0.2 mol l-1 [Fe2+] = 0.05 mol 1-1What would be the free-energy change generated by the import of one mole of Na+ from a concentration of 10 mM to 150 mM with a membrane potential of −25 mV at 37°C? Give your answer without units and to one decimal place. F = 96.5 kJ/V•molCompute for the loading dose of Gentamicin for a 135-pound patient if the target plasma concentration is 0.06mg/L. The hypothetical volume of distribution of the drug is 0.36L/kg body weight
- Considering the values in the following table, what relationship can be observed between the amount of sucrose and the water potential? What would you expect to happen if the amount of sucrose continues to increase? saccharose (M) solution (MPa) 0 0.1 0.15 0.2 0.25 0.3 0.35 0.4 0.45 0.5 0.6 0 -0.2478 -0.3717 -0.4956 -0.6195 -0.7434 -0.8673 -0.9912 -1.1151 -1.239 -1.4868 test mass differential 1 (g) 0.0333 0.0201 0.0143 0.0126 -0.0127 -0.0432 -0.0756 -0.0951 -0.0985 -0.1278 -0.1535 test mass differential 2 (g) 0.05555 0.0355 0.0275 0.015 0.002 -0.0295 -0.0755 -0.093 -0.124 -0.148 -0.1765Using the Nernst equation, calculate the equilibrium potential for Ca2 and for C1 from the following sets of data: a. Given [ Ca2+ ]0=1mM,[ Ca2+ ]i=100nM, find Eca2+ b. Given [ Cl- ]0=110mM,[ Cl- ]i=100mM, find EclTo calculate the total amount of drug in a solution How much sodium bicarbonate is there in a 200 mL infusion sodium bicarbonate 8.4% w/v?
- If experimental determinations of Kp at different temperatures for a given equilibrium in the temperature range 20-40 °C are fitted to the function shown below: In K, = a T2+c In() (a = 123.5 K?; = 23.6) %3D Answer the following questions: Calculate Kw at 5°C, assuming that AH° is temperature independent.The biexponential equation for a two compartment model drug is C1,t = 50.0e-1.64t + 20.0e-0.147t. The drug is administered as a rapid IV bolus at t = 0. After 2.00 hours how many mg/l will the drug concentration in the central compartment be.Calculate the effective quantity (g) of sodium chloride related to tonicity in 100 mL of an intravenous fluid labeled "5% dextrose in 0.45% sodium chloride," and indicate whether the solution is isotonic, hypotonic, or hypertonic.