4. Different populations of mouse L-cells that lack cadherins were transfected with either E- cadherin or P-cadherin. If cells expressing E-cad are mixed with those expressing P-cad, they segregate into distinct balls of cells (A in figure). However, if cells expressing different levels of the same cadherin are mixed, they form a single ball, with the high expressing cells in the center B in the figure). (A) E-cadherin SORTING OUT P-cadherin (B) low P-cadherin SORTING OUT high P-cadherin Why do the cells expressing different levels of cadherin segregate as in (B) in the figure, and why not into two separate balls, or one ball with a different organization (randomly mixed, or high expressors on the outside)?

4. Different populations of mouse L-cells that lack cadherins were transfected with either E- cadherin or P-cadherin. If cells expressing E-cad are mixed with those expressing P-cad, they segregate into distinct balls of cells (A in figure). However, if cells expressing different levels of the same cadherin are mixed, they form a single ball, with the high expressing cells in the center B in the figure). (A) E-cadherin SORTING OUT P-cadherin (B) low P-cadherin SORTING OUT high P-cadherin Why do the cells expressing different levels of cadherin segregate as in (B) in the figure, and why not into two separate balls, or one ball with a different organization (randomly mixed, or high expressors on the outside)?

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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