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2. The following double stranded segment of DNA is part of a protein coding gene. The segments in uppercase letters (ACTG) represent the exons. The segments in lowercase letters (acgt) represent introns. The lower strand is the template strand that is used by the RNA polymerase to make an RNA transcript. Draw or write-out a) the sequence of the primary transcript and b) the mature mRNA resulting from this stretch of DNA. GCTAAATGGCAaaattgccggatgacGCACATTGACTCGGaatcgaGGTCAGATGC CGATTTACCGTtttaacggcctactgCGTGTAACTGAGCCttagctCCAGTCTACG

2. The following double stranded segment of DNA is part of a protein coding gene. The segments in uppercase letters (ACTG) represent the exons. The segments in lowercase letters (acgt) represent introns. The lower strand is the template strand that is used by the RNA polymerase to make an RNA transcript. Draw or write-out a) the sequence of the primary transcript and b) the mature mRNA resulting from this stretch of DNA. GCTAAATGGCAaaattgccggatgacGCACATTGACTCGGaatcgaGGTCAGATGC CGATTTACCGTtttaacggcctactgCGTGTAACTGAGCCttagctCCAGTCTACG

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Exercise: Understanding DNA Transcription and mRNA Splicing** **Question 2:** The text describes a double-stranded segment of DNA that is part of a protein-coding gene. - **Exons** are represented by uppercase letters (ACTG). - **Introns** are represented by lowercase letters (acgt). - The **lower strand** of this DNA sequence is the template strand used by RNA polymerase to synthesize an RNA transcript. **Task:** - **a)** Write out the sequence of the primary RNA transcript. - **b)** Write out the sequence of the mature mRNA after splicing. **DNA Sequence:** ``` GCTAAATGGCAaattgccgatgacgCACATTGACTGCGAATcgaGGTGCAGATGC CGATTTACCGTTttaacggcctactgCGTTGAACTGACGttagctCCAGTCTACG ``` **Explanation for Students:** - The **primary transcript** is formed by transcribing the template strand (lower strand) into RNA, replacing thymine (T) with uracil (U). - After transcription, **splicing** removes the introns (lowercase segments) from the primary transcript to create the mature mRNA, which contains only exons. Students should pay attention to the instructions for identifying exons and introns and how transcription and splicing work.
Transcribed Image Text:**Exercise: Understanding DNA Transcription and mRNA Splicing** **Question 2:** The text describes a double-stranded segment of DNA that is part of a protein-coding gene. - **Exons** are represented by uppercase letters (ACTG). - **Introns** are represented by lowercase letters (acgt). - The **lower strand** of this DNA sequence is the template strand used by RNA polymerase to synthesize an RNA transcript. **Task:** - **a)** Write out the sequence of the primary RNA transcript. - **b)** Write out the sequence of the mature mRNA after splicing. **DNA Sequence:** ``` GCTAAATGGCAaattgccgatgacgCACATTGACTGCGAATcgaGGTGCAGATGC CGATTTACCGTTttaacggcctactgCGTTGAACTGACGttagctCCAGTCTACG ``` **Explanation for Students:** - The **primary transcript** is formed by transcribing the template strand (lower strand) into RNA, replacing thymine (T) with uracil (U). - After transcription, **splicing** removes the introns (lowercase segments) from the primary transcript to create the mature mRNA, which contains only exons. Students should pay attention to the instructions for identifying exons and introns and how transcription and splicing work.
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