Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 45, Problem 13TYK
Summary Introduction
To review:
Myasthenia gravis, an autoimmune disease, may develop into cats, dogs, and humans. Individuals suffering with the disease experience severe fatigue with even small levels of exertion, drooping of facial muscles, and trouble keeping their eyelids open.
Introduction:
Myasthenia gravis is a neuromuscular type of autoimmune disease. Autoimmune disease is a medical condition in which antibodies are formed against self-molecules in the cell, mostly against the receptors. The antibodies are formed against acetylcholine receptors in the synapse of neurons and muscle cells.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 45 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 45.1 - Prob. 1SBCh. 45.1 - What are the key differences between innate...Ch. 45.2 - Prob. 1SBCh. 45.2 - What processes specifically cause each...Ch. 45.2 - Prob. 3SBCh. 45.2 - Prob. 4SBCh. 45.3 - How, in general, do antibody-mediated and...Ch. 45.3 - Prob. 2SBCh. 45.3 - Prob. 3SBCh. 45.3 - What is clonal selection?
Ch. 45.3 - Prob. 5SBCh. 45.4 - Prob. 1SBCh. 45.4 - Prob. 2SBCh. 45.5 - Compare invertebrate and mammalian immune...Ch. 45 - Prob. 1TYKCh. 45 - Which of the following is not a component of the...Ch. 45 - Prob. 3TYKCh. 45 - Prob. 4TYKCh. 45 - Prob. 5TYKCh. 45 - Prob. 6TYKCh. 45 - Prob. 7TYKCh. 45 - Prob. 8TYKCh. 45 - After Sally punctured her hand with a dirty nail,...Ch. 45 - Prob. 10TYKCh. 45 - Prob. 11TYKCh. 45 - Prob. 12TYKCh. 45 - Prob. 13TYKCh. 45 - Prob. 14TYKCh. 45 - Apply Evolutionary Thinking Defensins are found in...Ch. 45 - Prob. 1ITDCh. 45 - Prob. 2ITDCh. 45 - Prob. 3ITDCh. 45 - Prob. 4ITD
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