Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Question
Chapter 45, Problem 11TYK
Summary Introduction
To review:
HIV attacks helper T cells and macrophages, and wreaks havoc on the immune system. The altered impact when the virus attacks only the macrophages.
Introduction:
HIV (human immune deficiency virus) is a pathogen of humans. This virus as suggested by name; this virus causes the immune system deficient by attacking the immune cells (helper T cells and macrophages). The person infected with HIV becomes susceptible to other diseases as the immunity of that person is reduced.
Expert Solution & Answer
Trending nowThis is a popular solution!
Students have asked these similar questions
Identify the statement that does not provide accurate evidence as to why HIV is so lethal.
a.
During the course of infection, HIV increases immune activation by altering intestinal physiology to let more microbes into the blood supply.
b.
Immune evasion increases in many infections due to HIV virions evolving new and unrecognizable epitopes (antigens).
c.
In many individuals the virus population evolves to use different receptors to gain access to a greater diversity of host immune cells.
d.
HIV causes enhanced replication and proliferation of T cells, which allows the immune system to work better at defending against pathogens.
Considering that each virus must bind to a specific cell surface receptor for attachment, explain how you would create a drug that prevents viral attachment.
This is a hypothetical scenario.
A recently emerged virus has been transmitting and mutating rapidly in humans throughout the world. If a vaccine that stops transmission of all current circulating variants of the virus in humans is utilized and herd immunity is achieved throughout the world, would this essentially stop 1) further transmission of the virus; 2) further mutation of the virus, respectively? Why/why not? Please answer the question succinctly and in bullet points!
Chapter 45 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 45.1 - Prob. 1SBCh. 45.1 - What are the key differences between innate...Ch. 45.2 - Prob. 1SBCh. 45.2 - What processes specifically cause each...Ch. 45.2 - Prob. 3SBCh. 45.2 - Prob. 4SBCh. 45.3 - How, in general, do antibody-mediated and...Ch. 45.3 - Prob. 2SBCh. 45.3 - Prob. 3SBCh. 45.3 - What is clonal selection?
Ch. 45.3 - Prob. 5SBCh. 45.4 - Prob. 1SBCh. 45.4 - Prob. 2SBCh. 45.5 - Compare invertebrate and mammalian immune...Ch. 45 - Prob. 1TYKCh. 45 - Which of the following is not a component of the...Ch. 45 - Prob. 3TYKCh. 45 - Prob. 4TYKCh. 45 - Prob. 5TYKCh. 45 - Prob. 6TYKCh. 45 - Prob. 7TYKCh. 45 - Prob. 8TYKCh. 45 - After Sally punctured her hand with a dirty nail,...Ch. 45 - Prob. 10TYKCh. 45 - Prob. 11TYKCh. 45 - Prob. 12TYKCh. 45 - Prob. 13TYKCh. 45 - Prob. 14TYKCh. 45 - Apply Evolutionary Thinking Defensins are found in...Ch. 45 - Prob. 1ITDCh. 45 - Prob. 2ITDCh. 45 - Prob. 3ITDCh. 45 - Prob. 4ITD
Knowledge Booster
Similar questions
- Consider the separate stages of an animal virus life cycle. Assemble a short list of structures and processes that are unique to the virus and would make good drug targets for an antiviral agent. Explain your rationale for each choice.arrow_forwardHow does having this additional information make the vaccine more effective?arrow_forwardViruses can easily mutate exchange genetic material, mechanisms referred to as antigenic drift and antigenic shift. These changes allow the virus to evade the immune system defenses. Match each term with the correct definition Antigenic drift [ Choose ] [Choose ] Different strains of a virus or strain of different viruses, combine and form a new strain that now has a mixture of the surface antigens Antigenic shift The virus changes genetically by accumulating mutations within the genes that code for antibody-binding sitesarrow_forward
- Refer to figures and compare and contrast how both viruses use surface receptors to evade an immune reaction and neutralizingantibodies.arrow_forwardwith HIV, explain the mechanism of intracellular infection and the role of reverse transcriptase. What would you explain about the process? What is the significance of the CD4+ count? ( Discuss the meaning of various ranges of CD4 counts.) List 5 opportunistic infections AND describe data to suggest whether or not a patient has such an infection.arrow_forward1) 286 individuals were newly diagnosed with Human Immunodeficiency Virus in 2018 in Minnesota. Of these individuals, 76% were male. HIV is an enveloped, ssRNA virus_ Baltimore classification VI. This virus targets CD4+ cells. CD4 refers to a glycoprotein which serves as a co-receptor for T-cells, located on T-helper and T-reg immune cells. a) What part of the HIV virus allows for specificity to CD4+ cells?arrow_forward
- Read in eTextbook - Chapter 19 page 405 - Replicative Cycles of Animal Viruses especially see Figure 19.8 The replicative cycle of an enveloped RNA virus After reading you need to do 2 things - see A and B below. A) Post an original post answering the 2 questions. using at least 6-8 sentences per answer. question 1: what are 2 good potential targets in SARS-CoV2 virus to stop it from functioning ? (HINT: Think antibodies targeting important viral proteins) question 2: what is the Pfizer Vaccine composed of? what does it target in SARS-CoV2 virus? Can you connect it to any concept from Ch 17 in your course?arrow_forwardDescribe the ways in which each of the following pathogens can disarm their host’s immune system or manipulate it to their own advantage:a. Pathogenic strains of Staphylococcusb. Enveloped virusesarrow_forwardGiven what we know about HIV, describe the impact of this virus on humoral and cellular immunity. [hint - HIV targets CD4 cells; how will this impact an immune response]arrow_forward
- What happens in the thymus? Propose an explanation that the changes in the thymus makes senior citizens less capable of fighting off new pathogens, like COVID-19 viruses when they first appeared in the US in 2020.arrow_forwardDescribe a drug therapy that has been used for patients infected with SARS COV2. What does it target/disrupt - a part of the virus itself, a viral process, the host immune response?arrow_forwardConsider the events that occur in HIV infection. I. HIV undergoes molecular self assembly.II. The protein gp120 binds to CD4.III. The HIV genome is incorporated into the host cell genome.IV. Reverse transcriptase is activated.V. The lipid envelope of HIV fuses with the T cell membrane. What is the correct sequence of the numbered events? I > III > V > IV > II IV > II > I > V > III II > V > IV > III > I III > I > II > IV > Varrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning