Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Question
Chapter 45, Problem 11TYK
Summary Introduction
To review:
HIV attacks helper T cells and macrophages, and wreaks havoc on the immune system. The altered impact when the virus attacks only the macrophages.
Introduction:
HIV (human immune deficiency virus) is a pathogen of humans. This virus as suggested by name; this virus causes the immune system deficient by attacking the immune cells (helper T cells and macrophages). The person infected with HIV becomes susceptible to other diseases as the immunity of that person is reduced.
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This is a hypothetical scenario.
A recently emerged virus has been transmitting and mutating rapidly in humans throughout the world. If a vaccine that stops transmission of all current circulating variants of the virus in humans is utilized and herd immunity is achieved throughout the world, would this essentially stop 1) further transmission of the virus; 2) further mutation of the virus, respectively? Why/why not? Please answer the question succinctly and in bullet points!
A researcher performs an experiment where he infects 2 mice (Mouse A and Mouse B) with herpes simplex virus (HSV). To measure the cytotoxicity of CD8+ T cells from Mouse A, he isolates CD8+ T cells from Mouse A and co-cultures them with a mixture of HSV-infected spleen cells from Mouse B. A day later, he checks the co-culture, but none of the infected spleen cells from Mouse B have been killed.
What could explain this observation?
a.Mouse B does not express the invariant chain (Ii)
b.Mouse A and Mouse B express different MHC alleles
c.Mouse A does not express TLR2/6
d.HSV immunoevasins block MHC-II expression
Consider the separate stages of an animal virus life cycle. Assemble a short list of structures and processes that are unique to the virus and would make good drug targets for an antiviral agent. Explain your rationale for each choice.
Chapter 45 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 45.1 - Prob. 1SBCh. 45.1 - What are the key differences between innate...Ch. 45.2 - Prob. 1SBCh. 45.2 - What processes specifically cause each...Ch. 45.2 - Prob. 3SBCh. 45.2 - Prob. 4SBCh. 45.3 - How, in general, do antibody-mediated and...Ch. 45.3 - Prob. 2SBCh. 45.3 - Prob. 3SBCh. 45.3 - What is clonal selection?
Ch. 45.3 - Prob. 5SBCh. 45.4 - Prob. 1SBCh. 45.4 - Prob. 2SBCh. 45.5 - Compare invertebrate and mammalian immune...Ch. 45 - Prob. 1TYKCh. 45 - Which of the following is not a component of the...Ch. 45 - Prob. 3TYKCh. 45 - Prob. 4TYKCh. 45 - Prob. 5TYKCh. 45 - Prob. 6TYKCh. 45 - Prob. 7TYKCh. 45 - Prob. 8TYKCh. 45 - After Sally punctured her hand with a dirty nail,...Ch. 45 - Prob. 10TYKCh. 45 - Prob. 11TYKCh. 45 - Prob. 12TYKCh. 45 - Prob. 13TYKCh. 45 - Prob. 14TYKCh. 45 - Apply Evolutionary Thinking Defensins are found in...Ch. 45 - Prob. 1ITDCh. 45 - Prob. 2ITDCh. 45 - Prob. 3ITDCh. 45 - Prob. 4ITD
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