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Immunoglobulins (Igs) are also termed as antibodies. Igs are glycoprotein molecules made by plasma cells (white blood cells). Igs play an important role in the immune response by particularly identifying and binding to antigens, like bacteria and viruses and thereby aids in its destruction. All Igs possess basic structure made up of four polypeptide chains, namely two identical heavy chains and two identical light chains. Both light (L) chains and heavy (H) chains encompass two different regions, such as the constant regions and the variable regions. The variable (V) regions (VL and VH) of an antibody possess different amino acid sequences. These regions fold together thereby forming the antigen-binding sites. The four chains are arranged in a Y with a hinge region. The stalk of the Y is known as crystallizable fragments (Fc). The top of the Y composed of two antigen-binding fragments (Fab), which attaches to compatible epitopes.
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Chapter 34 Solutions
Prescott's Microbiology
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- O Macmillan Learning You have 0.100 M solutions of acetic acid (pKa = 4.76) and sodium acetate. If you wanted to prepare 1.00 L of 0.100 M acetate buffer of pH 4.00, how many milliliters of acetic acid and sodium acetate would you add? acetic acid: mL sodium acetate: mLarrow_forwardHow does the cost of food affect the nutritional choices people make?arrow_forwardBiopharmaceutics and Pharmacokinetics:Two-Compartment Model Zero-Order Absorption Questions SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)arrow_forward
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