You generate a transgenic mouse line with a lox-stop-lox sequence upstream of a dominant-negative Notch fused to GFP. Upon crossing this mouse with another mouse line expressing ectoderm-specific Cre, what would you expect for the phenotype of neuronal differentiation in the resulting embryos?
You generate a transgenic mouse line with a lox-stop-lox sequence upstream of a dominant-negative Notch fused to GFP. Upon crossing this mouse with another mouse line expressing ectoderm-specific Cre, what would you expect for the phenotype of neuronal differentiation in the resulting embryos?
Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
Chapter51: Animal Development
Section: Chapter Questions
Problem 13TYU
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You generate a transgenic mouse line with a lox-stop-lox sequence upstream of a dominant-negative Notch fused to GFP. Upon crossing this mouse with another mouse line expressing ectoderm-specific Cre, what would you expect for the
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