DAD 1 DAD 2 MOM Twin 1 Twin 2 Who is the daddy? Dad 1 fathered both twins. Dad 2 fathered both twins. Dad 1 is the father of twin 1 and Dad 2 is the father of twin 2. Neither Dad 1 or Dad 2 could have fathered these twins.
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- Assume that the ratio of females to males is 1:1. A couple already has two daughters and no sons. If they plan to have a total of six children, what is the probability that they will have four more girls? (a) (b) (c) 116 (d) 132 (e) 164A couple who wishes to have children visits you, a genetic counselor. There is a history of a deleterious recessive trait in males in the womans family but not in the mans family. The couple is convinced that because his family shows no history of this genetic disease, they are not at risk of having affected children. What steps would you take to assess this situation and educate the couple?Jan is concerned about using ART. She wants to be the genetic mother and have Darryl be the genetic father of any children they have. What methods of ART would you recommend to this couple? Jan, a 32-year-old woman, and her husband, Darryl, have been married for 7 years. They have attempted to have a baby on several occasions. Five years ago, they had a first-trimester miscarriage, followed by an ectopic pregnancy later the same year. Jan continued to see her OB/GYN physician for infertility problems but was very dissatisfied with the response. After four miscarriages, she went to see a fertility specialist, who diagnosed her with severe endometriosis and polycystic ovarian disease (detected by hormone studies). The infertility physician explained that these two conditions were hampering her ability to become pregnant and thus making her infertile. She referred Jan to a genetic counselor. At the appointment, the counselor explained to Jan that one form of endometriosis (MIM 131200) can be a genetic disorder, and that polycystic ovarian disease can also be a genetic disorder (MIM 184700) and is one of the most common reproductive disorders among women. The counselor recommended that a detailed family history of both Jan and Darryl would help establish whether Jans problems have a genetic component and whether any of her potential daughters would be at risk for one or both of these disorders. In the meantime, Jan is taking hormones, and she and Darryl are considering alternative modes of reproduction. Using the information in Figure 16.4, explain the reproductive options that are open to Jan and Darryl.
- Redgreen color blindness is an X-linked recessive disorder in humans. Your friend is the daughter of a color-blind father. Her mother had normal color vision, but her maternal grandfather was color-blind. What is the probability that your friend is color-blind? (a) 1 (b) (c) (d) (e) 0One of your best friends tells you that she and her husband think she might be pregnant. She feels she can wait until shes several months along before finding an obstetrician. You think she could use some medical advice sooner, and you suggest she discuss her plans with a physician as soon as possible. What kinds of health issues might you be concerned about?If your father were diagnosed with an inherited disease that develops around the age of 50, would you want to be tested to find out whether you would develop this disease? If so, when would you want to be tested? As a teenager or sometime in your 40s? If not, would you have children?
- Does the phenotype indicated by the red circles and squares in this pedigree show an inheritance pattern that is autosomal dominant, autosomal recessive, or X-linked?Figure 8.16 What ratio of offspring would result from a cross between a white-eyed male and a female that is heterozygous for red eye color?Bill and Marie each have flat feet, long eyelashes, and achoo syndrome (chronic sneezing). All are dominant traits. The genes for these traits each have two alleles, which we can designate as follows: Bill is heterozygous for each trait. Marie is homozygous for all of them. What is Bill's genotype? What is Maries genotype? If they have four children, what is the probability that each child will have the same phenotype as the parents? What is the probability that a child will have short lashes, high arches, and no achoo syndrome?
- Zoe has cystic fibrosis. Which of the following is the most likely explanation? Zoe probably inherited one faulty allele from her father, who is a earner, and one normal allele from her mother. Zoe probably inherited one faulty allele from her mother, who must also have cystic fibrosis, and one normal allele from her father. Zoe must have inherited faulty alleles from both parents, both of whom must also have cystic fibrosis, Zoe must have inherited faulty alleles from both parents, both of whom are earners.The offspring of the cross AA aa are ________. a. all AA b. all aa c. all Aa d. half are AA and half are aaG6PD deficiency is an X-Linked recessive disorder. When people who have this disorder eat fava beans, they have a dangerous acute reaction in which a large number of their red blood cells rupture. A mother has the disorder; the father does not. What is the chance that any child of this union will have the trait?