The effect on the structure of hemoglobin by the substitution of valine in place of glutamic acid is to be explained. Concept introduction: Hemoglobin is an oxygen carrying pigment made up of four heme groups that surrounds the globin group. Heme Group contains an iron atom which is responsible for the red color to the molecule. In sickle-cell disease, hemoglobin S is found. It is a type of anemia in which oxygen is in short supply and all the red blood cells become sickle-shaped. Hence, it is known as sickle-cell anemia. To determine: The effect on the structure of hemoglobin by the substitution of valine in place of glutamic acid.
The effect on the structure of hemoglobin by the substitution of valine in place of glutamic acid is to be explained. Concept introduction: Hemoglobin is an oxygen carrying pigment made up of four heme groups that surrounds the globin group. Heme Group contains an iron atom which is responsible for the red color to the molecule. In sickle-cell disease, hemoglobin S is found. It is a type of anemia in which oxygen is in short supply and all the red blood cells become sickle-shaped. Hence, it is known as sickle-cell anemia. To determine: The effect on the structure of hemoglobin by the substitution of valine in place of glutamic acid.
Solution Summary: The author explains the effect on the structure of hemoglobin by the substitution of valine in place of glutamic acid.
Interpretation: The effect on the structure of hemoglobin by the substitution of
valine in place of glutamic acid is to be explained.
Concept introduction: Hemoglobin is an oxygen carrying pigment made up of four
heme groups that surrounds the
globin group.
Heme Group contains an iron atom which is responsible for the red color to the molecule. In sickle-cell disease, hemoglobin S is found. It is a type of anemia in which oxygen is in short supply and all the red blood cells become sickle-shaped. Hence, it is known as sickle-cell anemia.
To determine: The effect on the structure of hemoglobin by the substitution of
valine in place of glutamic acid.
If a reaction occurs, what would be the major products? Please include a detailed explanation as well as a drawing showing how the reaction occurs and what the final product is.
Would the following organic synthesis occur in one step? Add any missing products, required catalysts, inorganic reagents, and other important conditions. Please include a detailed explanation and drawings showing how the reaction may occur in one step.
(a) Sketch the 'H NMR of the following chemical including the approximate
chemical shifts, the multiplicity (splitting) of all signals and the integration
(b) How many signals would you expect in the 13C NMR?
CH3
Chapter 22 Solutions
Student Solutions Manual for Zumdahl/Zumdahl/DeCoste?s Chemistry, 10th Edition
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