Concept explainers
Interpretation:
The reaction obtained by coupling hydrolysis of
Concept Introduction:
Exergonic: The reaction is considered as exergonic if energy released since the reactants loses its energy making the free energy more negative hence making it spontaneous reaction.
Endergonic: The reaction is considered as endergonic if it needs more energy means that activation energy is much higher making the reaction non spontaneous.
Favorable Reaction: They release free energy which in turn used to do work. The products will have lower energy than reactants of the reaction shows that stable products are obtained hence the value of
The tendency for reaction proceed toward product side before reaching equilibrium will increases as more amount of free energy released.
Hydrolysis: The reaction in which chemical compound is breakdown in presence of water is termed as hydrolysis. Here water serves as one reactant.
Phosphorylation: It involves transfer of phosphate group from inorganic/organic phosphate to another chemical compound.
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Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
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- Assume that you have a solution of 0.1 M glucose 6-phosphate. To this solution you add the enzyme phosphoglucomutase, which catalyzes the reaction: glucose-6-P ⇔ glucose-1-P ∆G°′ = +1.7 kJ/mol (a) Does this reaction proceed at all as written at 25 °C, and if so, what are the final concentrations of glucose 6-P and glucose 1-P? (b) What effect would omitting the enzyme have on the reaction. Be specific. (c) Under what cellular conditions, if any, would this reaction continuously produce glucose 1-P at a high rate?arrow_forwardThe mechanism involved in the reaction catalyzed by phosphoglyceromutase is known to involve a phosphorylatedenzyme intermediate. If 3-phosphoglycerate is radioactively labeledwith 32P, the product of the reaction, 2-phosphoglycerate, does nothave any radioactive label. Design a mechanism to explain these facts.arrow_forwardIn order to function as an oxidative phosphorylation uncoupler (page 648), 2,4-dinitrophenol must act catalytically, not stoichio- metrically. What does this mean? Identify and discuss an important implication of this conclusion.arrow_forward
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