Synthetic approach to synthesize the given compound without using ester of the form given below via Claisen-Condensation is to proposed Concept introduction: Caisen condensation can be self Claisen condensation or cross Claisen condensation. In self condensation, two precursors are identical while in cross, they are different. Here, retrosynthesis of the product suggests that it is a product of cross Claisen condensation. In cross condensation, one precursor should be an ester or ketone that cannot form enolate, and another which can form enolate.

Question

Want to see the full answer?

Answer 1

Question

Chapter 21, Problem 21.26P

Interpretation Introduction

Interpretation:

Synthetic approach to synthesize the given compound without using ester of the form given below via Claisen-Condensation is to proposed

Concept introduction:

Caisen condensation can be self Claisen condensation or cross Claisen condensation. In self condensation, two precursors are identical while in cross, they are different.

Here, retrosynthesis of the product suggests that it is a product of cross Claisen condensation. In cross condensation, one precursor should be an ester or ketone that cannot form enolate, and another which can form enolate.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

111 Carbonyl Chem Choosing reagants for a Wittig reaction What would be the best choices for the missing reagents 1 and 3 in this synthesis? 1. PPh3 3 1 2 2. n-BuLi • Draw the missing reagents in the drawing area below. You can draw them in any arrangement you like. Do not draw the missing reagent 2. If you draw 1 correctly, we'll know what it is. • Note: if one of your reagents needs to contain a halogen, use bromine. Explanation Check Click and drag to start drawing a structure. × ©2025 McGraw Hill LLC. All Rights Reserved. Terms of Use

A student proposes the transformation below in one step of an organic synthesis. There may be one or more reactants missing from the left-hand side, but there are no products missing from the right-hand side. There may also be catalysts, small inorganic reagents, and other important reaction conditions missing from the arrow. • Is the student's transformation possible? If not, check the box under the drawing area. . If the student's transformation is possible, then complete the reaction by adding any missing reactants to the left-hand side, and adding required catalysts, inorganic reagents, or other important reaction conditions above and below the arrow. • You do not need to balance the reaction, but be sure every important organic reactant or product is shown. + T X O O лет-ле HO OH HO OH This transformation can't be done in one step.

Determine the structures of the missing organic molecules in the following reaction: X+H₂O H* H+ Y OH OH Note: Molecules that share the same letter have the exact same structure. In the drawing area below, draw the skeletal ("line") structures of the missing organic molecules X and Y. You may draw the structures in any arrangement that you like, so long as they aren't touching. Click and drag to start drawing a structure. X S