Introduction To Genetic Analysis
12th Edition
ISBN: 9781319114787
Author: Anthony J.F. Griffiths, John Doebley, Catherine Peichel, David A. Wassarman
Publisher: W. H. Freeman
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Chapter 2, Problem 56.11P
Summary Introduction
To determine: The uncertainty and the certainty of the genotypes that are mentioned in the problem.
Introduction: The genotype is a part of any individual's genetic makeup. The genotype helps in describing the
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Salim and Sara are contemplating having children, but Salim’s brother has galactosemia and Sara’s great-grandmother also had galactosemia. Sara has a sister who has three children, none of whom is affected.
What is the probability that Salim and Sara’s first child will have galactosemia? Explain your calculations.
Salim and Sara are contemplating having children, but Salim’s brother has galactosemia and Sara has a sister who has three children, one of whom is affected. Sara dad has no history in his family of any sign of the diease and it is assumed to be homozygous normal. What is the probability that salim and saras first child will have galactosemia?
Salim and Sara are contemplating having children, but Salim’s brother has galactosemia and Sara has a sister who has three children, none of whom is affected. Sara dad has no history in his family of any sign of the diease and it is assumed to be homozygous normal. What is the probability that salim and saras first child will have galactosemia?
Chapter 2 Solutions
Introduction To Genetic Analysis
Ch. 2 - Prob. 1PCh. 2 - Prob. 2PCh. 2 - Prob. 3PCh. 2 - Prob. 4PCh. 2 - Prob. 5PCh. 2 - Prob. 6PCh. 2 - Prob. 7PCh. 2 - Prob. 8PCh. 2 - Prob. 9PCh. 2 - Prob. 10P
Ch. 2 - Prob. 11PCh. 2 - Prob. 12PCh. 2 - Prob. 13PCh. 2 - Prob. 14PCh. 2 - Prob. 15PCh. 2 - Prob. 17PCh. 2 - Prob. 18PCh. 2 - Prob. 19PCh. 2 - Prob. 20PCh. 2 - Prob. 21PCh. 2 - Prob. 22PCh. 2 - Prob. 23PCh. 2 - Prob. 24PCh. 2 - Prob. 25PCh. 2 - Prob. 26PCh. 2 - Prob. 27PCh. 2 - Prob. 28PCh. 2 - Prob. 29PCh. 2 - Prob. 30PCh. 2 - Prob. 31PCh. 2 - Prob. 32PCh. 2 - Prob. 33PCh. 2 - Prob. 34PCh. 2 - Prob. 35PCh. 2 - Prob. 36PCh. 2 - Prob. 37PCh. 2 - Prob. 38PCh. 2 - Prob. 39PCh. 2 - Prob. 40PCh. 2 - Prob. 41PCh. 2 - Prob. 42PCh. 2 - Prob. 43PCh. 2 - Prob. 44PCh. 2 - Prob. 45PCh. 2 - Prob. 46PCh. 2 - Prob. 47PCh. 2 - Prob. 48PCh. 2 - Prob. 49PCh. 2 - Prob. 50PCh. 2 - Prob. 51PCh. 2 - Prob. 52PCh. 2 - Prob. 53PCh. 2 - Prob. 54PCh. 2 - Prob. 55PCh. 2 - Prob. 56PCh. 2 - Prob. 56.1PCh. 2 - Prob. 56.2PCh. 2 - Prob. 56.3PCh. 2 - Prob. 56.4PCh. 2 - Prob. 56.5PCh. 2 - Prob. 56.6PCh. 2 - Prob. 56.7PCh. 2 - Prob. 56.8PCh. 2 - Prob. 56.9PCh. 2 - Prob. 56.10PCh. 2 - Prob. 56.11PCh. 2 - Prob. 56.12PCh. 2 - Prob. 56.13PCh. 2 - Prob. 56.14PCh. 2 - Prob. 56.15PCh. 2 - Prob. 57PCh. 2 - Prob. 58PCh. 2 - Prob. 59PCh. 2 - Prob. 60PCh. 2 - Prob. 61PCh. 2 - Prob. 62PCh. 2 - Prob. 63PCh. 2 - Prob. 64PCh. 2 - Prob. 65PCh. 2 - Prob. 67PCh. 2 - Prob. 68PCh. 2 - Prob. 69PCh. 2 - Prob. 70PCh. 2 - Prob. 71PCh. 2 - Prob. 72PCh. 2 - Prob. 73PCh. 2 - Prob. 74PCh. 2 - Prob. 75PCh. 2 - Prob. 76PCh. 2 - Prob. 77PCh. 2 - Prob. 78PCh. 2 - Prob. 79PCh. 2 - Prob. 80PCh. 2 - Prob. 81PCh. 2 - Prob. 82PCh. 2 - Prob. 83PCh. 2 - Prob. 84PCh. 2 - Prob. 85PCh. 2 - Prob. 86PCh. 2 - Prob. 87PCh. 2 - Prob. 88PCh. 2 - Prob. 89PCh. 2 - Prob. 90PCh. 2 - Prob. 91PCh. 2 - Prob. 1GSCh. 2 - Prob. 2GSCh. 2 - Prob. 3GS
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- Kate and her husband are both heterozygous for galactosemia gene. If Kate and her husband have four children, how many of their children are likely to have galactosemia?arrow_forwardAcatalasia is caused by a rare autosomal recessive gene. In heterozygous condition catalase activity is decreased slightly. A woman with a normal catalase activity have a husband with low catalase activity. What is the probability of children birth without anomaly in the family, if grandparents from both sides have reduced activity of catalase? Diagram the cross and mention the genotypes of all individuals in the family?arrow_forwardSalim and Sara are contemplating having children, but Salim’s brother has galactosemia and Sara’s great-grandmother also had galactosemia. Sara has a sister who has three children, none of whom is affected.a. Construct a genetic pedigree for this family showing the possible genotype of each member.b. What is the probability that Salim and Sara’s first child will have galactosemia? Explain your calculations.arrow_forward
- Hemophilia is caused by an X-linked recessive mutation in humans. If a man whose paternal uncle (father's brother) was a hemophiliac marries a woman whose brother is also a hemophiliac, what is the probability that their first child will have hemophilia? (Assume that no other cases of hemophilia exist in the pedigree.) 1/3 0 1/8 0 1/4 1/2arrow_forwardCystic fibrosis in humans is caused by mutations in a single gene and is inherited as an autosomal (non-sex chromosome) recessive trait. An unaffected couple has two children. The first child has cystic fibrosis, and the second child is unaffected. What is the probability that the second child is a carrier (heterozygous) for the mutation that causes the disease? 2/3 1 1/2 3/4arrow_forwardThalassemia is an inherited anemic disorder in humans. Affected individuals exhibit either a minor anemia or a major anemia. Assuming that only a single gene pair and two alleles are involved in the inheritance of these conditions, is thalassemia a dominant or recessive disorder?arrow_forward
- The accompanying pedigree shows a family in which one child (II-1) has an autosomal recessive condition. On the basis of this fact alone, provide the following information. 1) What is the chance that among the three children in generation II who have the dominant phenotype, one of them is AAAA and two of them are AaAa? (Hint: Consider all possible orders of genotypes.) Express your answer to two decimal places.arrow_forwardIn humans, six fingers (F) is dominant to five fingers (f). Assume both parents are heterozygous for six fingers.c) What are the different gametes each parent can produce?arrow_forward*Cystic fibrosis is a rare autosomal recessive condition. phenotypically normal man whose father had cystic fibrosis marries a phenotypically normal woman from outside the family.² a) Draw the pedigree as far as described. b) If the frequency of heterozygotes in the general population is 1/50, what is the probability that the couple's first child will have cystic fibrosis? c) If the first child does have cystic fibrosis, what is the probability that the second child will be normal?arrow_forward
- Alleles of a single gene control whether individuals have a "hitchhiker's thumb" or "straight thumb." You are studying the inheritance of hitchhiker's thumb (straight thumb is dominant) in your family. Assuming that this trait is inherited on an autosome (ie, not a sex-chromosome), please answer which of the following outcomes ARE POSSIBLE under normal circumstances. (Choose all that apply.) 1) Two parents have straight thumb, but they have a child with hitchhiker's thumb. 2) Two parents have hitchhiker's thumb, but they have a child with straight thumb. 3) Mother has straight thumb, father has hitchhiker's thumb, child is homozygous dominant for the allele. 4) Mother has straight thumb, father has hitchhiker's thumb. They have one child with straight thumb, another child with hitchhiker's thumb.arrow_forwardThis is a typical pedigree for a family that carries neurofibromatosis. Is individual I-2 most likely homozygous or heterozygous? Why? Explain.arrow_forwardAssume that color blindness is a recessive character on the X chromosome. A man and woman with normal vision have the following offspring: a daughter with normal vision who has one color-blind son and one normal son; a daughter with normal vision who has six normal sons; and a color-blind son who has a daughter with normal vision. What are the probable genotypes of all individuals?arrow_forward
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