A.
To draw: The pedigree in the given case.
Introduction: Cystic fibrosis is a hereditary disease generated due to the mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
B.
To determine: The probability of the couple's first child to have cystic fibrosis
Introduction: Cystic fibrosis is the consequence of changes in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. About1,800 distinct mutations have been known that can induce cystic fibrosis. People acquiring two recessive CFTR alleles possess the disease.
C.
To determine: The probability of the second child being normal if the first child does have cystic fibrosis.
Introduction: Cystic fibrosis is an autosomal recessive disease, and this is the kind of condition one can acquire if both of the parents share a particular copy of a recessive gene. A recessive gene is one that can be concealed by a dominant gene.
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Introduction To Genetic Analysis
- A sex-linked recessive allele rg causes a red-green colorblindness in humans. A normal woman whose father was colorblind marries a colorblind man. A. What genotypes are possible for the mother of the colorblind man? B. What are the chances that the first child from this marriage will be a colorblind boy? C. Of the girls born from this union, what proportion can be expected to be colorblind? D. Of all the children of these parentsarrow_forwardTay–Sachs disease is caused by recessive alleles on anautosome. In which case(s) could two parents with anormal phenotype have a child with Tay–Sachs?a. Both parents are homozygous for a Tay–Sachs allele.b. Both parents are heterozygous for a Tay–Sachsallele.c. One parent is homozygous for a Tay–Sachs allele,and the other is heterozygous.arrow_forwarda. Is the trait indicated by the solid symbols inherited in a dominant or recessive manner? (2) b. Give a definitive reason for your answer in (a). (This reason should not be skips a generation or doesn’t skip a generation). c. Assign genotypes for individuals III-3 in both pedigrees.arrow_forward
- Assume that one of Merida's sons, who is heterozygous for orange hair color, married a girl that was also heterozygous. Create a Punnett square to show the possibilities that would result if they had children. a. List the possible genotypes and phenotypes for their children. b. What are the chances of a child with orange hair? c. What are the chantes of a child with yellow?arrow_forwardThe following diagram shows a hypothetical diploid cell. The recessive allele for albinism is represented by a, and d represents the recessive allele for deafness. The normal alleles for these conditions are represented by A and D, respectively. Please use the symbols A, a, D and d as appropriate to help me understand your answer. a а D 1. According to Mendel's principal of segregation, what is segregating in this cell? 2. According to Mendel's principle of independent assortment, what is independently assorting in this cell? 3. What is the phenotype of this individual? © Cengage Learningarrow_forwardThe petal color of a species of flowers is inherited along Mendelian ratios. A cross of two plants with red flowers produces 1,068 plants with red flowers and 390 plants with yellow flowers. A. Propose a model to explain the inheritance of red and yellow flowers. B. Determine the probability of producing a plant with yellow flowers when a heterozygous plant with red flowers is crossed with a homozygous plant with yellow flowers. B I U 三 三 of 22 Answered tv MacBook Air 吕口 F3 D00 F4 # $ & 3 4 5 6 7 Q W E Yarrow_forward
- The chart below is showing 4 generations of a family that is affected by a hereditary disease. a. Is the disorder being tracked dominant or recessive? How do you know? b. There is only one possible genotype for person C. True or False? c. What are the possible genotypes for person A? d. What are the possible genotypes for person B?, e. If two people with the same genotypes as person C's spouse and person A's spouse had a child, what is the probability that the child will be affected by this genetic disorder? (draw a Punnett square using the correct genotypes to help you). % chance offspring will be affected % chance offspring will not be affectedarrow_forwardTay-Sachs disease is a rare human disease in which toxic substances accumulate in nerve cells. The recessive allele responsible for the disease is inherited in a simple Mendelian manner. For unknown reasons, the allele is more common in populations of Ashkenazi Jews of eastern Europe. A woman is planning to marry her first cousin, but the couple discovers that their shared grandfather’s sister died in infancy of Tay-Sachs disease.a. Draw the relevant parts of the pedigree, and show all the genotypes as completely as possible. b. What is the probability that the cousins’ first child will have Tay-Sachs disease, assuming that all people who marry into the family are homozygous normal?arrow_forwardThe achoo syndrome (sneezing in response to bright light) and trembling chin (triggered by anxiety) are both dominant traits in humans. A. What is the probability that the first child of parents heterozygous for both the achoo gene and trembling chin will have achoo syndrome but lack trembling chin? B. If the same couple decides to have five children what is the probability that at most three will have achoo syndrome? C. If the same couple decides to have five children what is the probability that at most three will have achoo syndrome?arrow_forward
- A poultry grower has 2 breeds of chicken, averaging 9 and 5 lbs. inweight. The F1 of the cross between is quite uniform, averaging 7lbs. Of the F2 progeny, 0.4% is as heavy as either parent. a. How much does each effective allele contribute to weight? b. What is the number of polygenes pairs involved in thesecrosses? c. If only those with an average weight of 6-8 lbs. are marketable, whatpercentage of the offspring will yield profit for the grower?arrow_forward. The pedigree below was obtained for a rare kidney disease.a. Deduce the inheritance of this condition, stating your reasons. b. If persons 1 and 2 marry, what is the probability that their first child will have the kidney disease?arrow_forwardTightly curled hair is caused by a dominant autosomal gene in humans. This trait is rare among northern Europeans. If a curly-haired northern European marries a person with straight hair, what phenotypes (and in what proportions) are expected in the offspring? A. ½ curly (because the curly-haired individual is most likely heterozygous), ½ straight B. ½ curly (because the curly-haired individual is most likely homozygous), ½ straight hair C. all curly (because the curly-haired individual is most likely heterozygous) D. ¾ curly (because the curly-haired individual is most likely heterozygous), ¼ straight hair E. None of the choices that are provided is correctarrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning