Concept explainers
a.
To determine: The condition of inheritance in the given diagram.
Introduction: Genetic abnormalities are those that occupy the chromosomal location and produce the non-functional proteins. The abnormalities can be caused due either to mutation in a single
b.
To determine: The probability of the first child to be diseased when person 1 and person 2 in the given pedigree get married.
Introduction: The gene transferred from parents may be dominant as well as the recessive. The expression of the genes or alleles determines the type of abnormalities in the progenies, which may be of four types, autosomal dominant and autosomal recessive, X-linked dominant and X-linked recessive.
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Introduction To Genetic Analysis
- Situation: Guinevere decides to trace the inheritance of her blood type through her family, all the way back to her great-grandmother Natalia. Guinevere's great-grandmother Natalia, has type A blood. Natalia and her husband Claude have five children-three sons, Miguel (who has blood type A), Mark (who has blood type B) and David (who has type AB blood); a daughter (Jane) with type O blood and another daughter (Janella) with type A blood. Jane marries a man and they have two sons (Marco and Polo) who both are blood type A and a daughter (Mara) who has blood type B; Janella on the other hand marries a man and together have three sons (one with blood type A, one with AB, and one with O). Miguel marries a woman with type O blood and together they have three children (daughter Frances and son Albert who both have type A blood, and a son Mike with type O blood). Mike marries Johann and together they have one daughter, Guinevere. Guinevere knows that her parents both have the same blood type,…arrow_forwardc) What blood types could be observed in children born to a woman who has blood type A and a man who has blood type AB? Draw a Punnett square to prove your answers.arrow_forwardPedigree chart *questions are on the image attachedarrow_forward
- Refer to the pedigree below which shows inheritance for achondroplasia (dwarfism), a dominantly inherited trait (denoted as D), which are the darkened circles and squares. Dwarfism (darkened shapes) are dominantly inherited, while normal height is recessively inherited (hh). Based on the pedigree, what is the correct genotype for individual #II-6? Dominant Autosomal Pedigree 2 II 2 3 II 1 2 3 6 9 10 Dd DD DD or Dd ddarrow_forwardUsing the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?arrow_forwardDuchenne muscular dystrophy (DMD) is an example of an X-linked trait. This is a neuromuscular disease that causes muscles to slowly dehydrate, leading to paralysis. The disease allele is recessive (Xd) and the normal allele is dominant (XD). A female that is a carrier for DMD has kids with a normal male. Complete this cross on scratch paper and then answer the questions. A. What is the chance (%) that these two parents will have a kid with DMD? B. Their first child is a son. What is the chance (%) that he will have DMD? Hint: Look at only the male offspring when you answer this question.arrow_forward
- If two individuals with blood type AB marry, what are the odds that each of their children will have the AB blood type? Draw a Punnett square to answer the question. A father and mother have the following blood types, AO and BB, respectively. Create a Punnett square to determine the possible blood types that their children might have. a. What are the possible blood types of the children? b. Which parent could donate blood to any of the children?arrow_forwardLois, who recently had her karyotype performed, was shown the following figure from her family physician. Lois does not suffer or show any signs of any genetic condition. Peter Lois A. What type of abnormality is shown in Lois' karyotype and explain why she does not have a genetic condition? B. Lois and Peter are expecting their 1st child. What is the probabilitv that the child will have a genetic condition due to the translocation? Show your workarrow_forwardIs the mode of inheritance autosomal or sex-related? Justify your answer. What is the probabilty that the individual with an asterisk will have a daughter affected by the trait?arrow_forward
- Please consider the pedigree below. There are no cases of false paternity. The ABO blood group phenotypes of individuals who marry into the family are a true reflection of their ABO genotypes. image attached I a. Which individual/s definitely has/have Bombay phenotype in the descendants of I-1 and I-2? b. What are the genotypes of individuals I-1 and II-2 at the ABO and H loci?arrow_forwardThe genetic disease hemophilia A is a sex-linked trait. Jane has an uncle on her father's side of the family who has hemophilia A, her father does not have hemophilia A. On Jane's mother's side of the family there has never been a case of hemophilia A. Should Jane be concerned about passing the gene for hemophilia A to her own children? Explain your answer.arrow_forwardPlease help with parts a and b please. a) You are a farmer taking your squash to the farmer’s market. Green squash happens to be very popular with your customers and can be sold at a higher price than white or yellow squash. Which of the following squash plant crosses will give you a higher number of green squash to bring to the market? Show your work 1. AaBb (white) x Aabb (yellow) or 2. aaBb (white) x Aabb (yellow) b) What type of epistasis does this squash coloration likely demonstrate and why?arrow_forward
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