A.
To determine: The cases where the genotype is in doubt by assigning Mendelian allelic symbols for the affected and unaffected condition and apply them to the individuals in generations V, VI and VII
Introduction: Arterial Calcification of Infancy or GACI is a rare genetic condition inherited by an autosomal recessive inheritance pattern. The affected gene can be passed from generation to generation. People can transfer the gene and not exhibit any symptoms.
b.
To determine: The siblings in generation VI in terms of mendelian ratio.
Introduction:
c.
To determine: The probability that all five children would be affected in a family with five children born to parents who are both unaffected carriers of the mutant allele
Introduction: Mutant type is a phenotype produced due to a mutation. Also, phenotype additional than the wild type expresses as a mutant type. Also, here one or several mutant type
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Introduction To Genetic Analysis
- State the conclusions reached by Mendel in his work on the inheritance of characteristics. Explain how each of the following deviates from these conclusions: a. Autosomal linkage b. Sex-linked (X-linked) inheritance c. Polygenic (multiple-gene) inheritancearrow_forwardGlucose-6-phosphate dehydrogenase (G6PD) deficiency is a disorder that affects the normal function of red blood cells and can eventually lead to anemia. The trait is controlled by a recessive allele found on 4. the X chromosome. An affected son was born to a man and woman who were unaffected. The woman's mother was affected while the father was normal. a. Indicate the gene notation. b. Give the genotypes of the affected boy's parents. Derive the genotypic and phenotypic ratios for the offspring. Show and label your solutions properly. What is the probability that they will have a phenotypically normal daughter as their first child? C. d.arrow_forwardPorphyria is a genetic disorder caused by the inability to properly metabolize a component of hemoglobin. King George III is suspected to have been afflicted with this disorder. Assume that both George and his Queen suffered from this disorder and they had one afflicted child and one normal child. Is porphyria inherited in a dominant or recessive fashion? What must be the genotype of both George and his Queen? Using punnett square, show ALL work used to achieve your answer.arrow_forward
- Below is a pedigree chart for a family that has a history of Alkaptonuria. Individuals infected with this condition can have darkened skin, brown urine, and can suffer from joint damage and other complications. Given this pedigree answer the following questions. Given the data in the pedigree chart is this genetic condition autosomal dominant or autosomal recessive? What are the genotypes for #1, #2, and #3? If either of the 4th generation "aa" females were to mate with a homozygous dominant male would any of their offspring illustrate the phenotype? Why or why not?arrow_forwardIn a paternity suit, a woman with type O blood claims that a man with type AB blood is the father of her type O baby. List the genetypes of the mom, man, and baby. Can the woman prove he is the father or can he is not? Why or why not? If the accused man was type A insyead of type AB, what would be his possible genotypes? Could the woman prove he is the father? Can the man prove he is not the father? Why or why not?arrow_forwardWhich of the following does not have an environmental factor thataffects the distribution of the phenotype? a. phenylketonuria c. heightb. skin color d. Marfan syndromearrow_forward
- In a well-publicized paternity case, the following facts were determined: the mother, a beautiful, twice-convicted axe murderer, is blood type A. Her child, Lizzie, is type O and the alleged father, a mild-mannered felon convicted of check fraud, is type B. On the last day of the trial, another father – a missionary worker with blood type O is identified. Which of the two could be Lizzie’s father? Use the space below to support your conclusion. I am really confused with the queshtion and need help finding the answer and how to prove can somone explain the answer and show it in a punnet sqaure pleasearrow_forwardUse the pedigree to answer the questions that follow. Make sure you put your answer in the correct blank. A) AB В 1 5 II A A AB B A AB A 3 5 6 7 8 II A A B 2 3 5 6 a) State the possible blood type(s) of individual I-4 b) State the possible blood type(s) of individual I-6 c) State the possible genotype(s) of individual Il-5 d) State the possible genotype(s) of individual II-6 e) Determine the percentage chance that couple Il-4 and Il-5 have another child that has type O blood 2.arrow_forwardGive typing answer with explanation and conclusionarrow_forward
- In this figure, the black circles and squares indicate a genetic disease. A. Based on the pedigree in the figure, does this gene appear to be inherited in a dominant or recessive manner? Explain your prediction. B. Use the letter a to indicate a disease allele and the letter A to indicate a normal allele. Predict the genotypes of the original parents. C. What percentage of the offspring of the original parents would you expect to have the disease? D. Predict the genotype of the partner of the diseased daughter in generation II. Justify your prediction.arrow_forwardPlease complete table 15.2 with diagrams that illustrate the appropriate components. Which blood cells are co dominant? Which are recessive? Complete a punnet square A based upon a cross between individuals with the following genotypes : AO & BO.arrow_forwardFor this problem, use the information given in problem 15. A young woman with blood type O gave birth to a baby with blood type O. In a court case, she claims that a certain young man is the father of her child. The man has type A blood. Could he be the father? Can it be proven on this evidence alone that he is the father? ^Need answers to that one, including genotype, phenotype gametes and punnett square. This is question 15 as a little background dont need this solved . In humans, there are three alleles for blood type: A, B, and O. The allele for blood type A and the allele for blood type B show incomplete dominance. A person with both alleles has blood type AB. Both A and B dominate type O. A person with alleles for blood types A and O marries someone with alleles for blood types B and O. List the types of blood their offspring could have and the probability for each blood type in the offspringarrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning